Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2414234263', 'doi': 'https://doi.org/10.1080/03007995.2016.1198755', 'title': 'Paliperidone palmitate: Japanese postmarketing mortality results in patients with schizophrenia', 'display_name': 'Paliperidone palmitate: Japanese postmarketing mortality results in patients with schizophrenia', 'publication_year': 2016, 'publication_date': '2016-06-06', 'ids': {'openalex': 'https://openalex.org/W2414234263', 'doi': 'https://doi.org/10.1080/03007995.2016.1198755', 'mag': '2414234263', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27264496'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/03007995.2016.1198755', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206643269', 'display_name': 'Current Medical Research and Opinion', 'issn_l': '0300-7995', 'issn': ['0300-7995', '1473-4877'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111419469', 'display_name': 'Phillip F. Pierce', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Phillip Pierce', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076376973', 'display_name': 'Srihari Gopal', 'orcid': 'https://orcid.org/0000-0001-5254-2192'}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Srihari Gopal', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020650497', 'display_name': 'Adam Savitz', 'orcid': 'https://orcid.org/0000-0001-8868-3704'}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Adam Savitz', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102001970', 'display_name': 'Hong Qiu', 'orcid': 'https://orcid.org/0000-0001-5625-864X'}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hong Qiu', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009489218', 'display_name': 'Takahito Hino', 'orcid': None}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takahito Hino', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, Japan;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091488942', 'display_name': 'Michélle Busch', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michelle Busch', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045471307', 'display_name': 'Akiko Fujino', 'orcid': None}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akiko Fujino', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, Japan;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081125396', 'display_name': 'Maju Mathews', 'orcid': 'https://orcid.org/0000-0003-4144-1008'}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maju Mathews', 'raw_affiliation_strings': ['Janssen Global Medical Affairs, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Global Medical Affairs, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059466131', 'display_name': 'Takeshi Katsu', 'orcid': None}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takeshi Katsu', 'raw_affiliation_strings': ['Janssen Pharmaceutical Medical Affairs, Japan'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Medical Affairs, Japan', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065389298', 'display_name': 'Yoshikazu Maeda', 'orcid': 'https://orcid.org/0000-0002-3040-5549'}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshikazu Maeda', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, Japan;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102974005', 'display_name': 'Masayoshi Takahashi', 'orcid': 'https://orcid.org/0000-0001-5392-9057'}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masayoshi Takahashi', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, Japan;', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5043115868', 'display_name': 'David Hough', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151386', 'display_name': 'Janssen (United States)', 'ror': 'https://ror.org/05af73403', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522', 'https://openalex.org/I4210151386']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David Hough', 'raw_affiliation_strings': ['Janssen Pharmaceutical Research and Development, USA;'], 'affiliations': [{'raw_affiliation_string': 'Janssen Pharmaceutical Research and Development, USA;', 'institution_ids': ['https://openalex.org/I4210151386']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5111419469'], 'corresponding_institution_ids': ['https://openalex.org/I4210151386'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.133, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 12, 'citation_normalized_percentile': {'value': 0.709801, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '32', 'issue': '10', 'first_page': '1671', 'last_page': '1679'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11943', 'display_name': 'Pharmacovigilance and Adverse Drug Reactions', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/3005', 'display_name': 'Toxicology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11950', 'display_name': 'Cardiovascular Syncope and Autonomic Disorders', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/paliperidone-palmitate', 'display_name': 'Paliperidone Palmitate', 'score': 0.9183947}, {'id': 'https://openalex.org/keywords/postmarketing-surveillance', 'display_name': 'Postmarketing surveillance', 'score': 0.5110117}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.96075225}, {'id': 'https://openalex.org/C2908997079', 'wikidata': 'https://www.wikidata.org/wiki/Q27157250', 'display_name': 'Paliperidone Palmitate', 'level': 4, 'score': 0.9183947}, {'id': 'https://openalex.org/C2776412080', 'wikidata': 'https://www.wikidata.org/wiki/Q7431605', 'display_name': 'Schizophrenia (object-oriented programming)', 'level': 2, 'score': 0.61395127}, {'id': 'https://openalex.org/C197636746', 'wikidata': 'https://www.wikidata.org/wiki/Q7234359', 'display_name': 'Postmarketing surveillance', 'level': 3, 'score': 0.5110117}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.36797354}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.35757238}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.33073735}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.32836407}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.3007719}, {'id': 'https://openalex.org/C2780494398', 'wikidata': 'https://www.wikidata.org/wiki/Q208144', 'display_name': 'Antipsychotic', 'level': 3, 'score': 0.22862774}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/03007995.2016.1198755', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206643269', 'display_name': 'Current Medical Research and Opinion', 'issn_l': '0300-7995', 'issn': ['0300-7995', '1473-4877'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27264496', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.89, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320337415', 'funder_display_name': 'Janssen Research and Development', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1505546093', 'https://openalex.org/W1785627328', 'https://openalex.org/W1875611908', 'https://openalex.org/W1932851251', 'https://openalex.org/W1995601667', 'https://openalex.org/W1999049281', 'https://openalex.org/W1999070612', 'https://openalex.org/W2009890917', 'https://openalex.org/W2018681387', 'https://openalex.org/W2018972399', 'https://openalex.org/W2019952252', 'https://openalex.org/W2022592863', 'https://openalex.org/W2026268014', 'https://openalex.org/W2032704604', 'https://openalex.org/W2035261866', 'https://openalex.org/W2037746562', 'https://openalex.org/W2038166742', 'https://openalex.org/W2041193152', 'https://openalex.org/W2041376702', 'https://openalex.org/W2042843923', 'https://openalex.org/W2055465804', 'https://openalex.org/W2061331619', 'https://openalex.org/W2064036552', 'https://openalex.org/W2067451344', 'https://openalex.org/W2072686355', 'https://openalex.org/W2077503410', 'https://openalex.org/W2084876139', 'https://openalex.org/W2105527159', 'https://openalex.org/W2113463828', 'https://openalex.org/W2129132454', 'https://openalex.org/W2138784551', 'https://openalex.org/W2140154855', 'https://openalex.org/W2146506439', 'https://openalex.org/W2149288810', 'https://openalex.org/W2150154702', 'https://openalex.org/W2153735883', 'https://openalex.org/W2157959378', 'https://openalex.org/W2167532647', 'https://openalex.org/W2171956687', 'https://openalex.org/W2194009663', 'https://openalex.org/W2327775854', 'https://openalex.org/W2414469982', 'https://openalex.org/W261240404', 'https://openalex.org/W3083225504', 'https://openalex.org/W4241183987'], 'related_works': ['https://openalex.org/W4313201498', 'https://openalex.org/W4211108626', 'https://openalex.org/W4206860231', 'https://openalex.org/W3200106728', 'https://openalex.org/W3002401687', 'https://openalex.org/W2954080763', 'https://openalex.org/W2529527732', 'https://openalex.org/W2400434151', 'https://openalex.org/W2093725234', 'https://openalex.org/W1985435777'], 'abstract_inverted_index': {'Paliperidone': [0], 'palmitate': [1], 'once-monthly': [2], 'injectable': [3], '(PP1M)': [4], 'is': [5], 'approved': [6], 'in': [7, 42, 89, 104, 137, 140, 158, 185, 204, 212, 227], 'Japan': [8, 138, 213], 'and': [9, 71, 114, 139, 171, 247], 'other': [10], 'countries': [11], 'for': [12], 'the': [13, 18, 39, 43, 67, 76, 105, 124, 145, 150, 181, 186, 190, 222, 228, 233, 237, 252], 'treatment': [14, 203], 'of': [15, 163, 180, 220, 224, 236], 'schizophrenia.': [16], 'During': [17], '6': [19], 'month': [20], 'Japanese': [21, 151, 205, 230], 'early': [22], 'postmarketing': [23], 'phase': [24], 'vigilance': [25], '(EPPV)': [26], 'period,': [27, 78, 154, 189], '32': [28, 146, 182], 'deaths': [29, 147], 'were': [30, 64, 74, 81, 157], 'reported.': [31], 'This': [32], 'report': [33], 'reviews': [34], 'potential': [35], 'contributing': [36], 'factors': [37, 170], 'to': [38, 60, 83, 217], 'fatal': [40, 183, 238, 255], 'outcomes': [41], 'PP1M-treated': [44], 'population.All': [45], 'spontaneously': [46], 'reported': [47, 148, 167], 'adverse': [48], 'events': [49, 73], 'following': [50], 'PP1M': [51, 88, 110, 152, 187, 202], 'use': [52], 'received': [53, 174], 'during': [54, 95, 133, 149], 'EPPV': [55, 77, 97, 153, 188, 231], 'from': [56, 198], '19': [57], 'November': [58], '2013': [59], '18': [61], 'May': [62], '2014': [63], 'entered': [65], 'into': [66], 'global': [68], 'safety': [69], 'database': [70], 'these': [72], 'analyzed.During': [75], '10,962': [79], 'patients': [80, 159], 'estimated': [82], 'have': [84], 'been': [85], 'treated': [86], 'with': [87, 123, 201, 254], 'Japan.': [90], 'The': [91, 207], 'mortality': [92, 125, 209, 225], 'reporting': [93, 210, 226], 'rate': [94, 193], 'this': [96, 178], 'period': [98], 'was': [99, 121], 'higher': [100, 208], 'than': [101], 'that': [102], 'observed': [103, 132, 191], 'US': [106], 'or': [107], 'globally': [108], 'after': [109], 'launch': [111], '(5.84,': [112], '0.43,': [113], '0.38': [115], 'per': [116, 129], '1000': [117, 130], 'patient-years,': [118], 'respectively),': [119], 'but': [120], 'consistent': [122], 'incidence': [126], 'rates': [127, 211], '(10.2': [128], 'person-years)': [131], 'interventional': [134], 'clinical': [135], 'studies': [136], 'observational': [141], 'patient': [142], 'cohorts.': [143], 'Of': [144], '19/32': [155], '(59.4%)': [156], 'over': [160], '50': [161], 'years': [162], 'age,': [164], '23/32': [165], '(71.9%)': [166], 'cardiovascular': [168, 241], 'risk': [169, 200, 242], '25/32': [172], '(78.1%)': [173], 'antipsychotic': [175, 249], 'polypharmacy.Based': [176], 'on': [177], 'review': [179], 'cases': [184, 253], 'death': [192], 'does': [194], 'not': [195], 'necessarily': [196], 'result': [197], 'a': [199, 218], 'patients.': [206], 'may': [214], 'be': [215], 'attributed': [216], 'variety': [219], 'factors:': [221], 'effectiveness': [223], 'unique': [229], 'program,': [232], 'advanced': [234], 'age': [235], 'cases,': [239], 'high': [240, 248], 'factors,': [243], 'multiple': [244], 'underlying': [245], 'diseases': [246], 'polypharmacy': [250], 'among': [251], 'outcomes.': [256]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2414234263', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 4}], 'updated_date': '2024-12-13T23:23:03.220393', 'created_date': '2016-06-24'}