Title: High-affinity binding of forskolin to rat brain membranes.
Abstract:High-affinity forskolin binding sites in brain membranes have been identified that have structure-activity characteristics compatible with forskolin's site of action at the adenylate cyclase enzyme. I...High-affinity forskolin binding sites in brain membranes have been identified that have structure-activity characteristics compatible with forskolin's site of action at the adenylate cyclase enzyme. It is proposed that these high-affinity binding sites are associated with an activated complex of the catalytic protein and the alpha s subunit. Quantitation of high-affinity forskolin binding sites may provide a direct measure of the amount of adenylate cyclase that has the potential to be regulated by stimulatory hormones and the Ns subunit.Read More
Publication Year: 1985
Publication Date: 1985-01-01
Language: en
Type: article
Indexed In: ['pubmed']
Access and Citation
Cited By Count: 45
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