Publication Information

{'id': 'https://openalex.org/W2412374991', 'doi': None, 'title': '[Protective effects of pomegranate polyphenols on cardiac function in rats with myocardial ischemia/reperfusion injury].', 'display_name': '[Protective effects of pomegranate polyphenols on cardiac function in rats with myocardial ischemia/reperfusion injury].', 'publication_year': 2012, 'publication_date': '2012-06-01', 'ids': {'openalex': 'https://openalex.org/W2412374991', 'mag': '2412374991', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22820568'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22820568', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100937497', 'display_name': 'Shuying Dong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I169351748', 'display_name': 'Bengbu Medical College', 'ror': 'https://ror.org/01f8qvj05', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I169351748']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shuying Dong', 'raw_affiliation_strings': ['Faculty of Pharmacy, Bengbu Medical College, China'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Pharmacy, Bengbu Medical College, China', 'institution_ids': ['https://openalex.org/I169351748']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010647321', 'display_name': 'Xuhui Tong', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xuhui Tong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100458878', 'display_name': 'Hao Liu', 'orcid': 'https://orcid.org/0000-0003-1938-8925'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Hao Liu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060439422', 'display_name': 'Qin Gao', 'orcid': 'https://orcid.org/0000-0002-7599-4295'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Qin Gao', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.255, 'has_fulltext': False, 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.76127, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '32', 'issue': '7', 'first_page': '924', 'last_page': '7'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12638', 'display_name': 'Pomegranate: compositions and health benefits', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12638', 'display_name': 'Pomegranate: compositions and health benefits', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9539, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13796', 'display_name': 'Neurological Disorders and Treatments', 'score': 0.9016, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/preload', 'display_name': 'Preload', 'score': 0.7459451}, {'id': 'https://openalex.org/keywords/malondialdehyde', 'display_name': 'Malondialdehyde', 'score': 0.73187065}, {'id': 'https://openalex.org/keywords/creatine-kinase', 'display_name': 'Creatine kinase', 'score': 0.61876714}, {'id': 'https://openalex.org/keywords/ventricular-pressure', 'display_name': 'Ventricular pressure', 'score': 0.54980046}, {'id': 'https://openalex.org/keywords/creatine', 'display_name': 'Creatine', 'score': 0.41350216}], 'concepts': [{'id': 'https://openalex.org/C48277249', 'wikidata': 'https://www.wikidata.org/wiki/Q1406926', 'display_name': 'Preload', 'level': 3, 'score': 0.7459451}, {'id': 'https://openalex.org/C2778401633', 'wikidata': 'https://www.wikidata.org/wiki/Q418661', 'display_name': 'Malondialdehyde', 'level': 3, 'score': 0.73187065}, {'id': 'https://openalex.org/C111566952', 'wikidata': 'https://www.wikidata.org/wiki/Q1303462', 'display_name': 'Cardiac function curve', 'level': 3, 'score': 0.6978046}, {'id': 'https://openalex.org/C2777318727', 'wikidata': 'https://www.wikidata.org/wiki/Q409464', 'display_name': 'Lactate dehydrogenase', 'level': 3, 'score': 0.67149055}, {'id': 'https://openalex.org/C36880943', 'wikidata': 'https://www.wikidata.org/wiki/Q409458', 'display_name': 'Creatine kinase', 'level': 2, 'score': 0.61876714}, {'id': 'https://openalex.org/C2780114680', 'wikidata': 'https://www.wikidata.org/wiki/Q1413991', 'display_name': 'Reperfusion injury', 'level': 3, 'score': 0.6043777}, {'id': 'https://openalex.org/C26635844', 'wikidata': 'https://www.wikidata.org/wiki/Q2002035', 'display_name': 'Ventricular pressure', 'level': 3, 'score': 0.54980046}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.53374946}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5230385}, {'id': 'https://openalex.org/C541997718', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemia', 'level': 2, 'score': 0.50075054}, {'id': 'https://openalex.org/C2775838275', 'wikidata': 'https://www.wikidata.org/wiki/Q410776', 'display_name': 'Superoxide dismutase', 'level': 3, 'score': 0.47874492}, {'id': 'https://openalex.org/C70899900', 'wikidata': 'https://www.wikidata.org/wiki/Q290439', 'display_name': 'Polyphenol', 'level': 3, 'score': 0.42667198}, {'id': 'https://openalex.org/C2779896295', 'wikidata': 'https://www.wikidata.org/wiki/Q223600', 'display_name': 'Creatine', 'level': 2, 'score': 0.41350216}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.3799961}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3761262}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.34971228}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.336787}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.30192578}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.29067403}, {'id': 'https://openalex.org/C178853913', 'wikidata': 'https://www.wikidata.org/wiki/Q1642137', 'display_name': 'Hemodynamics', 'level': 2, 'score': 0.27020988}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1582253}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.14531931}, {'id': 'https://openalex.org/C2778198053', 'wikidata': 'https://www.wikidata.org/wiki/Q181754', 'display_name': 'Heart failure', 'level': 2, 'score': 0.12856391}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.086600006}], 'mesh': [{'descriptor_ui': 'D029561', 'descriptor_name': 'Lythraceae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015428', 'descriptor_name': 'Myocardial Reperfusion Injury', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D059808', 'descriptor_name': 'Polyphenols', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003402', 'descriptor_name': 'Creatine Kinase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003402', 'descriptor_name': 'Creatine Kinase', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D007770', 'descriptor_name': 'L-Lactate Dehydrogenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007770', 'descriptor_name': 'L-Lactate Dehydrogenase', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015227', 'descriptor_name': 'Lipid Peroxidation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008315', 'descriptor_name': 'Malondialdehyde', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008315', 'descriptor_name': 'Malondialdehyde', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015428', 'descriptor_name': 'Myocardial Reperfusion Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015428', 'descriptor_name': 'Myocardial Reperfusion Injury', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D059808', 'descriptor_name': 'Polyphenols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013482', 'descriptor_name': 'Superoxide Dismutase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013482', 'descriptor_name': 'Superoxide Dismutase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22820568', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.55, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3030884728', 'https://openalex.org/W2412374991', 'https://openalex.org/W2389802938', 'https://openalex.org/W2375502836', 'https://openalex.org/W2364031491', 'https://openalex.org/W2363785174', 'https://openalex.org/W2359445454', 'https://openalex.org/W2355635028', 'https://openalex.org/W2349427933', 'https://openalex.org/W2031231673'], 'abstract_inverted_index': {'To': [0], 'determine': [1], 'the': [2, 20, 74, 78, 88, 91, 94, 115, 129, 133, 137, 154, 171, 176, 209, 236], 'protective': [3], 'effect': [4], 'of': [5, 93, 105, 117, 151, 153, 190, 212, 235], 'pomegranate': [6, 41, 178], 'polyphenols': [7, 206], 'on': [8], 'cardiac': [9, 82, 184, 210], 'function': [10, 185, 211], 'in': [11, 77, 218, 223], 'rats': [12, 24, 51, 75, 138, 213], 'with': [13, 132, 139, 170, 214, 220], 'myocardial': [14, 69, 237], 'ischemia/reperfusion': [15], '(I/R)': [16], 'injury': [17, 71, 216], 'and': [18, 39, 47, 114, 160, 193, 200, 230], 'explore': [19], 'possible': [21], 'mechanism.Fifty': [22], 'SD': [23], 'were': [25, 52, 84, 99], 'randomized': [26], 'into': [27], '5': [28], 'equal': [29], 'groups,': [30], 'including': [31], 'a': [32, 55, 64], 'sham-operated': [33, 79, 134], 'group,': [34, 38, 135, 174], 'an': [35], 'I/R': [36, 70, 140, 172, 215], 'model': [37, 173], '3': [40, 177], 'polyphenol': [42, 179], 'dose': [43], 'groups': [44, 180], '(150,': [45], '300,': [46], '600': [48], 'mg/kg).': [49], 'The': [50, 81], 'subject': [53], 'to': [54, 67, 101, 127], '45-min': [56], 'left': [57, 144, 155, 163], 'main': [58], 'coronary': [59], 'artery': [60], 'occlusion': [61], 'followed': [62], 'by': [63], '180-min': [65], 'reperfusion': [66], 'induce': [68], 'except': [72], 'for': [73], 'those': [76], 'group.': [80], 'functions': [83], 'monitored': [85], 'continuously': [86], 'during': [87], 'experiment.': [89], 'At': [90], 'end': [92], 'reperfusion,': [95], 'arterial': [96], 'blood': [97], 'samples': [98], 'obtained': [100], 'measure': [102], 'plasma': [103, 188], 'contents': [104, 189], 'lactate': [106], 'dehydrogenase': [107], '(LDH),': [108], 'creatine': [109], 'kinase': [110], '(CK),': [111], 'malondialdehyde': [112], '(MDA)': [113], 'activities': [116, 198], 'superoxide': [118], 'dismutase': [119], '(SOD).': [120], 'Triphenyltetrazolium': [121], 'chloride': [122], '(TTC)': [123], 'staining': [124], 'was': [125], 'used': [126], 'evaluate': [128], 'infarct': [130, 203], 'size.Compared': [131], 'all': [136, 175], 'showed': [141], 'significantly': [142, 161, 182], 'decreased': [143, 187], 'ventricular': [145, 156, 164], 'systolic': [146], 'pressure': [147, 157, 166], '(LVSP),': [148], 'maximal': [149], 'rates': [150], 'increase/decrease': [152], '(±dp/dtmax)': [158], '(P<0.01)': [159], 'increased': [162, 196], 'end-diastolic': [165], '(LVEDP)': [167], '(P<0.01).': [168], 'Compared': [169], 'had': [181], 'improved': [183], '(P<0.05),': [186], 'CK,': [191], 'LDH': [192], 'MDA': [194], '(P<0.01),': [195, 199], 'SOD': [197], 'obviously': [201], 'reduced': [202], 'size': [204], '(P<0.01).Pomegranate': [205], 'can': [207], 'protect': [208], 'probably': [217], 'association': [219], 'their': [221], 'actions': [222], 'enhancing': [224], 'oxygen': [225], 'free': [226], 'radical': [227], 'scavenging': [228], 'activity': [229], 'decreasing': [231], 'lipid': [232], 'peroxidative': [233], 'damage': [234], 'tissues.': [238]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2412374991', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-12-13T06:43:21.679118', 'created_date': '2016-06-24'}