Abstract: Overview Simon R. Cherry, Ramsey D. Badawi, and Jinyi Qi X-Ray Projection Imaging and Computed Tomography Kai Yang and John M. Boone Magnetic Resonance Imaging Jeff R. Anderson and Joel R. Garbow Ultrasound K. Kirk Shung Optical and Optoacoustic Imaging Adrian Taruttis and Vasilis Ntziachristos Radionuclide Imaging Pat B. Zanzonico Quantitative Image Analysis Hsiao-Ming Wu and Wen-Yih I. Tseng