Title: [Cloning genes, induced by x-ray irradiation in rat liver cells].
Abstract: The library of cDNAs synthesized on poly(A)+ mRNA derived from rat liver after total X-irradiation of animals has been obtained. cDNA-clones (p gamma clones) representing sequences inducibly transcribed as a result of radiation treatment were isolated by differential screening. The increased expression of p gamma mRNAs was observed during the period from 6 to 24 h after irradiation by 3-6 Gy dose. It was concluded that p gamma mRNAs do not code for the liver-specified proteins because these mRNAs are also present in the rat fibroblasts. We suggest that p gamma genes are involved in the pathways of DNA-repair system.
Publication Year: 1989
Publication Date: 1989-07-01
Language: en
Type: article
Indexed In: ['pubmed']
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