Publication Information

{'id': 'https://openalex.org/W2410689767', 'doi': None, 'title': 'The serological response of the chicken to a protein antigen in multiple emulsion oil adjuvant.', 'display_name': 'The serological response of the chicken to a protein antigen in multiple emulsion oil adjuvant.', 'publication_year': 1973, 'publication_date': '1973-12-01', 'ids': {'openalex': 'https://openalex.org/W2410689767', 'mag': '2410689767', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4202421', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1422999'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4202421', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052196637', 'display_name': 'I.D. Aitken', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'I. D. Aitken', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5052196637'], 'corresponding_institution_ids': [], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.21, 'has_fulltext': False, 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.585008, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '25', 'issue': '6', 'first_page': '957', 'last_page': '66'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11124', 'display_name': 'Protein purification and stability', 'score': 0.9881, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11124', 'display_name': 'Protein purification and stability', 'score': 0.9881, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12322', 'display_name': 'Animal health and immunology', 'score': 0.9848, 'subfield': {'id': 'https://openalex.org/subfields/3404', 'display_name': 'Small Animals'}, 'field': {'id': 'https://openalex.org/fields/34', 'display_name': 'Veterinary'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9776, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/precipitin', 'display_name': 'Precipitin', 'score': 0.85085785}, {'id': 'https://openalex.org/keywords/antibody-response', 'display_name': 'Antibody response', 'score': 0.7605369}, {'id': 'https://openalex.org/keywords/bovine-serum-albumin', 'display_name': 'Bovine serum albumin', 'score': 0.5509335}], 'concepts': [{'id': 'https://openalex.org/C133229898', 'wikidata': 'https://www.wikidata.org/wiki/Q7239484', 'display_name': 'Precipitin', 'level': 3, 'score': 0.85085785}, {'id': 'https://openalex.org/C3018913218', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody response', 'level': 3, 'score': 0.7605369}, {'id': 'https://openalex.org/C2777863537', 'wikidata': 'https://www.wikidata.org/wiki/Q357896', 'display_name': 'Adjuvant', 'level': 2, 'score': 0.71566933}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.6488508}, {'id': 'https://openalex.org/C45189115', 'wikidata': 'https://www.wikidata.org/wiki/Q502159', 'display_name': 'Serology', 'level': 3, 'score': 0.6234225}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.6184238}, {'id': 'https://openalex.org/C2778123984', 'wikidata': 'https://www.wikidata.org/wiki/Q187634', 'display_name': 'Emulsion', 'level': 2, 'score': 0.5795245}, {'id': 'https://openalex.org/C86807702', 'wikidata': 'https://www.wikidata.org/wiki/Q2620381', 'display_name': 'Bovine serum albumin', 'level': 2, 'score': 0.5509335}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.47068766}, {'id': 'https://openalex.org/C2776125364', 'wikidata': 'https://www.wikidata.org/wiki/Q169219', 'display_name': 'Albumin', 'level': 2, 'score': 0.44628733}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.42872757}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41115242}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40101302}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.38264462}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.34701854}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.31319284}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.18709582}], 'mesh': [{'descriptor_ui': 'D000276', 'descriptor_name': 'Adjuvants, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000917', 'descriptor_name': 'Antibody Formation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000941', 'descriptor_name': 'Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000941', 'descriptor_name': 'Antigens', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D002417', 'descriptor_name': 'Cattle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D004655', 'descriptor_name': 'Emulsions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005779', 'descriptor_name': 'Immunodiffusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008899', 'descriptor_name': 'Mineral Oil', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011234', 'descriptor_name': 'Precipitins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011234', 'descriptor_name': 'Precipitins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D012710', 'descriptor_name': 'Serum Albumin, Bovine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D012710', 'descriptor_name': 'Serum Albumin, Bovine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013156', 'descriptor_name': 'Splenectomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4202421', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.69, 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 14, 'referenced_works': ['https://openalex.org/W1501742503', 'https://openalex.org/W1603038171', 'https://openalex.org/W1998851721', 'https://openalex.org/W2010925541', 'https://openalex.org/W202980389', 'https://openalex.org/W2036655620', 'https://openalex.org/W2041421225', 'https://openalex.org/W2052280694', 'https://openalex.org/W2109566447', 'https://openalex.org/W2136986382', 'https://openalex.org/W2316161891', 'https://openalex.org/W2413087416', 'https://openalex.org/W2417600332', 'https://openalex.org/W2438984558'], 'related_works': ['https://openalex.org/W2405319530', 'https://openalex.org/W2129235755', 'https://openalex.org/W2090324576', 'https://openalex.org/W2061622709', 'https://openalex.org/W2057560402', 'https://openalex.org/W2033998433', 'https://openalex.org/W2021037397', 'https://openalex.org/W2011183043', 'https://openalex.org/W1768409271', 'https://openalex.org/W1665476043'], 'abstract_inverted_index': {'In': [0, 47], 'adult': [1], 'chickens': [2], 'administration': [3], 'of': [4, 7, 35, 66, 71, 100, 113, 142], '4': [5], 'mg': [6], 'bovine': [8], 'serum': [9, 52, 72], 'albumin': [10], 'as': [11], 'a': [12, 24, 64, 87, 95], 'multiple': [13], 'emulsion': [14], '(water-in-oil-in-water)': [15], 'by': [16, 86], 'the': [17, 39, 50, 101, 110, 121, 126, 134, 143], 's.c.,': [18], 'i.m.': [19], 'or': [20], 'i.p.': [21], 'route': [22], 'stimulated': [23], 'persistent': [25], 'precipitin': [26, 105], 'response': [27, 55], 'that': [28, 99], 'was': [29, 41, 57, 81], 'still': [30], 'detectable': [31, 149], 'in': [32, 77, 91, 133, 137, 147], 'nine': [33], 'out': [34], 'twelve': [36], 'birds': [37], 'when': [38], 'experiment': [40], 'terminated': [42], '286': [43], 'days': [44, 85], 'after': [45, 83, 154], 'injection.': [46, 155], 'each': [48], 'group': [49], 'mean': [51], 'total': [53], 'antibody': [54, 69, 92, 114], 'curve': [56], 'biphasic.': [58], 'An': [59], 'initial': [60, 102, 111], 'rapid': [61], 'response,': [62], 'reaching': [63, 94], 'peak': [65, 96], '350–500': [67], 'μg': [68], 'N/ml': [70], 'on': [73], 'day': [74], '7–9,': [75], 'declined': [76], 'fluctuating': [78], 'fashion': [79], 'and': [80, 108], 'succeeded': [82], '30–60': [84], 'slower': [88], 'sustained': [89], 'rise': [90], 'level,': [93], 'similar': [97], 'to': [98, 131, 139], 'response.\r\n\r\nSplenectomy': [103], 'impaired': [104], 'production,': [106], 'delayed': [107], 'suppressed': [109], 'phase': [112, 128], 'synthesis,': [115], 'but': [116], 'did': [117], 'not': [118], 'significantly': [119], 'alter': [120], 'second': [122], 'phase.': [123], 'Synthesis': [124], 'during': [125], 'secondary': [127], 'is': [129], 'considered': [130], 'proceed': [132], 'granulomata': [135], 'where,': [136], 'contrast': [138], 'other': [140], 'tissues': [141], 'body,': [144], 'antigen': [145], 'remains': [146], 'readily': [148], 'amounts': [150], 'for': [151], 'several': [152], 'weeks': [153]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2410689767', 'counts_by_year': [], 'updated_date': '2024-12-17T00:37:36.755876', 'created_date': '2016-06-24'}