Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2410203954', 'doi': 'https://doi.org/10.1152/ajplegacy.1966.210.6.1293', 'title': 'Preparation and study of fragments of single rabbit nephrons', 'display_name': 'Preparation and study of fragments of single rabbit nephrons', 'publication_year': 1966, 'publication_date': '1966-06-01', 'ids': {'openalex': 'https://openalex.org/W2410203954', 'doi': 'https://doi.org/10.1152/ajplegacy.1966.210.6.1293', 'mag': '2410203954', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/5923067'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajplegacy.1966.210.6.1293', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S204210209', 'display_name': 'American Journal of Physiology-Legacy Content', 'issn_l': '0002-9513', 'issn': ['0002-9513', '2163-5773'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5082521358', 'display_name': 'M. B. Burg', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Burg', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109447593', 'display_name': 'J. J. Grantham', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J Grantham', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053953732', 'display_name': 'Maurice Abramow', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Abramow', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5089918858', 'display_name': 'Jack Orloff', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J Orloff', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.189, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 791, 'citation_normalized_percentile': {'value': 0.998519, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '210', 'issue': '6', 'first_page': '1293', 'last_page': '1298'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.9777, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.9777, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11163', 'display_name': 'Organ Donation and Transplantation', 'score': 0.9058, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/human-physiology', 'display_name': 'Human physiology', 'score': 0.61869407}], 'concepts': [{'id': 'https://openalex.org/C2986265897', 'wikidata': 'https://www.wikidata.org/wiki/Q23852', 'display_name': 'Human physiology', 'level': 2, 'score': 0.61869407}, {'id': 'https://openalex.org/C42407357', 'wikidata': 'https://www.wikidata.org/wiki/Q521', 'display_name': 'Physiology', 'level': 1, 'score': 0.49978518}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37799305}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.34092712}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.1693215}], 'mesh': [{'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007684', 'descriptor_name': 'Kidney Tubules', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000618', 'descriptor_name': 'Aminohippuric Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000618', 'descriptor_name': 'Aminohippuric Acids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007684', 'descriptor_name': 'Kidney Tubules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010477', 'descriptor_name': 'Perfusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011188', 'descriptor_name': 'Potassium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011188', 'descriptor_name': 'Potassium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012964', 'descriptor_name': 'Sodium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012964', 'descriptor_name': 'Sodium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014882', 'descriptor_name': 'Water-Electrolyte Balance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajplegacy.1966.210.6.1293', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S204210209', 'display_name': 'American Journal of Physiology-Legacy Content', 'issn_l': '0002-9513', 'issn': ['0002-9513', '2163-5773'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/5923067', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4245098612', 'https://openalex.org/W2788277189', 'https://openalex.org/W2414101105', 'https://openalex.org/W2130076355', 'https://openalex.org/W2119695867', 'https://openalex.org/W2082860237', 'https://openalex.org/W2082067206', 'https://openalex.org/W2046158694', 'https://openalex.org/W1993764875', 'https://openalex.org/W1990804418'], 'abstract_inverted_index': {'ARTICLESPreparation': [0], 'and': [1, 14, 22, 83, 110, 132, 153, 183, 200, 206, 215, 227, 269, 279, 302, 311, 327, 340, 395, 445, 468, 489, 509, 595, 631, 646, 663, 678, 703, 751, 784, 818, 872, 888, 915, 926, 934, 968, 999, 1034, 1087, 1110, 1146, 1165, 1194, 1243, 1257, 1274, 1286, 1305, 1339, 1361, 1382, 1409, 1444, 1483, 1519, 1553, 1569, 1576, 1587, 1615, 1644, 1663, 1669, 1708, 1730, 1739, 1782, 1814, 1839, 1850, 1873, 1913, 1960, 1994, 2012, 2030, 2046, 2051, 2068, 2094, 2099, 2131, 2153, 2159, 2170, 2182, 2195, 2226, 2266, 2292, 2329], 'study': [2, 1058], 'of': [3, 5, 48, 53, 92, 101, 126, 161, 171, 192, 202, 224, 234, 288, 296, 320, 329, 349, 361, 365, 404, 420, 437, 448, 457, 477, 518, 525, 540, 571, 588, 603, 610, 639, 650, 671, 683, 693, 711, 730, 760, 767, 776, 793, 800, 808, 827, 880, 923, 949, 957, 977, 985, 1007, 1014, 1021, 1043, 1051, 1059, 1077, 1084, 1092, 1118, 1126, 1155, 1163, 1203, 1213, 1223, 1230, 1240, 1265, 1272, 1313, 1347, 1354, 1391, 1400, 1418, 1453, 1460, 1491, 1498, 1501, 1528, 1535, 1561, 1571, 1580, 1596, 1610, 1624, 1633, 1653, 1677, 1717, 1725, 1748, 1755, 1762, 1790, 1806, 1823, 1830, 1847, 1882, 1892, 1921, 1969, 1976, 2003, 2010, 2039, 2049, 2076, 2092, 2108, 2122, 2140, 2167, 2203, 2210, 2220, 2235, 2246, 2249, 2275, 2282, 2300, 2311, 2314, 2337], 'fragments': [4], 'single': [6], 'rabbit': [7, 961, 1026, 1099, 1133, 1173, 1282, 1366, 1437, 1512, 1582, 1665, 1831, 1893, 1948, 2015, 2147, 2186, 2283], 'nephronsM': [8], 'Burg,': [9, 17], 'J': [10, 15, 18, 23], 'Grantham,': [11, 19], 'M': [12, 20], 'Abramow,': [13, 21], 'OrloffM': [16], 'OrloffPublished': [24], 'Online:01': [25], 'Jun': [26], '1966https://doi.org/10.1152/ajplegacy.1966.210.6.1293MoreSectionsPDF': [27], '(2': [28], 'MB)Download': [29], 'PDF': [30, 45], 'ToolsExport': [31], 'citationAdd': [32], 'to': [33, 41, 1168], 'favoritesGet': [34], 'permissionsTrack': [35], 'citations': [36], 'ShareShare': [37], 'onFacebookTwitterLinkedInEmailWeChat': [38], 'Previous': [39], 'Back': [40], 'Top': [42], 'Next': [43], 'Download': [44], 'FiguresReferencesRelatedInformationCited': [46], 'ByEffect': [47], 'luminal': [49], 'flow': [50, 852], 'on': [51, 173, 537, 652, 685, 1017, 1276, 1508, 2014, 2055, 2212], 'doming': [52], 'mpkCCD': [54], 'cells': [55, 725, 1609], 'in': [56, 177, 209, 238, 241, 253, 261, 374, 387, 416, 492, 548, 556, 562, 616, 654, 688, 720, 772, 804, 854, 892, 939, 953, 988, 1089, 1097, 1131, 1172, 1248, 1281, 1289, 1322, 1330, 1363, 1426, 1436, 1473, 1540, 1545, 1573, 1607, 1661, 1732, 1758, 1765, 1804, 1859, 1929, 2086, 2117, 2126, 2185, 2215, 2369], 'a': [57, 534, 851, 950, 1062, 1238, 1898, 1981], '3D': [58], 'perfusable': [59], 'kidney': [60, 1054, 1291, 1475, 1894, 2216], 'cortical': [61, 495, 721, 860, 1053, 1325, 1542, 1639, 2187], 'collecting': [62, 496, 722, 861, 1326, 1543, 1863, 2090, 2188, 2251], 'duct': [63, 723, 1544, 1693, 2091], 'modelJoshua': [64], 'L.': [65, 185, 281, 309, 342, 368, 397, 430, 470, 1700, 2228, 2321, 2323], 'Rein,': [66], 'Szilvia': [67], 'Heja,': [68], 'Daniel': [69], 'Flores,': [70], 'Rolando': [71], 'Carrisoza-Gaytán,': [72], 'Neil': [73], 'Y.': [74], 'C.': [75, 337, 658, 696, 1376, 1703, 2028], 'Lin,': [76], 'Kimberly': [77], 'A.': [78, 81, 112, 141, 564, 659, 697, 910, 1411, 1646, 1868, 2253, 2268, 2318], 'Homan,': [79], 'Jennifer': [80], 'Lewis,': [82], 'Lisa': [84, 739], 'M.': [85, 105, 181, 213, 217, 272, 542, 664, 699, 704, 840, 1183, 1216, 1255, 1306, 1740, 1741, 1962, 2320], 'Satlin25': [86], 'June': [87, 283, 842, 1842, 1877, 2034, 2162, 2270, 2366, 2372], '2020': [88, 115], '|': [89, 116, 158, 189, 221, 251, 285, 317, 346, 372, 401, 434, 474, 515, 546, 568, 600, 636, 668, 708, 757, 790, 824, 844, 877, 920, 974, 1004, 1040, 1074, 1115, 1152, 1200, 1220, 1262, 1310, 1344, 1388, 1415, 1450, 1488, 1525, 1558, 1593, 1621, 1650, 1674, 1714, 1745, 1787, 1820, 1844, 1879, 1918, 1937, 1966, 2000, 2036, 2073, 2105, 2137, 2164, 2200, 2232, 2272, 2297, 2334], 'American': [90, 159, 190, 222, 286, 318, 347, 402, 435, 475, 516, 526, 569, 601, 637, 669, 709, 758, 791, 825, 878, 921, 975, 1005, 1041, 1075, 1116, 1153, 1201, 1221, 1263, 1311, 1345, 1389, 1416, 1451, 1489, 1526, 1559, 1594, 1622, 1651, 1675, 1715, 1746, 1788, 1821, 1845, 1880, 1919, 1967, 2001, 2037, 2074, 2106, 2138, 2165, 2201, 2233, 2273, 2298, 2335, 2360], 'Journal': [91, 160, 191, 223, 287, 319, 348, 403, 436, 476, 517, 570, 602, 638, 670, 710, 759, 792, 826, 879, 922, 976, 1006, 1042, 1076, 1117, 1154, 1202, 1222, 1264, 1312, 1346, 1390, 1417, 1452, 1490, 1527, 1560, 1595, 1623, 1652, 1676, 1716, 1747, 1789, 1822, 1846, 1881, 1920, 1968, 2002, 2038, 2075, 2107, 2139, 2166, 2202, 2234, 2274, 2299, 2336], 'Physiology-Cell': [93, 438, 572, 1492, 1718, 1970], 'Physiology,': [94, 163, 194, 229, 254, 290, 322, 351, 406, 439, 479, 520, 573, 605, 641, 673, 713, 762, 795, 829, 845, 882, 928, 979, 1009, 1045, 1079, 1120, 1157, 1205, 1225, 1267, 1315, 1349, 1393, 1420, 1455, 1493, 1530, 1563, 1598, 1626, 1655, 1679, 1719, 1750, 1792, 1825, 1852, 1884, 1923, 1971, 2005, 2041, 2078, 2110, 2142, 2172, 2205, 2237, 2277, 2302, 2339], 'Vol.': [95, 119, 164, 195, 230, 255, 291, 323, 352, 377, 407, 440, 480, 521, 551, 574, 606, 642, 674, 714, 763, 796, 830, 846, 883, 929, 945, 980, 1010, 1046, 1080, 1121, 1158, 1206, 1226, 1268, 1316, 1350, 1394, 1421, 1456, 1494, 1531, 1564, 1599, 1627, 1656, 1680, 1720, 1751, 1793, 1826, 1853, 1885, 1924, 1940, 1972, 2006, 2042, 2079, 2111, 2143, 2173, 2206, 2238, 2278, 2303, 2340], '319,': [96], 'No.': [97, 121, 166, 197, 232, 293, 325, 354, 379, 409, 442, 482, 523, 553, 576, 608, 644, 676, 716, 765, 798, 832, 848, 885, 931, 947, 982, 1012, 1048, 1082, 1123, 1160, 1208, 1228, 1270, 1318, 1352, 1396, 1423, 1458, 1496, 1533, 1566, 1601, 1629, 1658, 1682, 1722, 1753, 1795, 1828, 1855, 1887, 1926, 1942, 1974, 2008, 2044, 2081, 2113, 2145, 2175, 2208, 2240, 2280, 2305, 2342], '1The': [98], 'Renal': [99], 'Physiology': [100, 375, 549], 'Pendrin-Positive': [102], 'Intercalated': [103], 'CellsSusan': [104], 'Wall,': [106], 'Jill': [107], 'W.': [108, 1107, 1147, 1302, 1383, 1589, 1617], 'Verlander,': [109], 'Cesar': [111], 'Romero29': [113], 'April': [114, 432, 1308], 'Physiological': [117, 527, 1938, 2361], 'Reviews,': [118, 1939], '100,': [120], '3Vibrodissociation': [122], 'method': [123, 2308], 'for': [124, 1056, 2309], 'isolation': [125, 2310], 'defined': [127, 2315], 'nephron': [128, 2316], 'segments': [129, 2121], 'from': [130, 299, 726, 836, 858, 2242, 2345], 'human': [131, 210, 1290], 'rodent': [133], 'kidneysElena': [134], 'Isaeva,*': [135], 'Mykhailo': [136], 'Fedoriuk,*': [137], 'Ruslan': [138], 'Bohovyk,': [139], 'Christine': [140, 903], 'Klemens,': [142], 'Sherif': [143], 'Khedr,': [144], 'Daria': [145], 'Golosova,': [146], 'Vladislav': [147], 'Levchenko,': [148], 'Ashraf': [149], 'El-Meanawy,': [150], 'Oleg': [151], 'Palygin,': [152], 'Alexander': [154], 'Staruschenko7': [155], 'November': [156, 706, 918, 1113, 1150, 1198, 1218, 2103], '2019': [157, 188, 220], 'Physiology-Renal': [162, 193, 289, 321, 350, 405, 478, 519, 604, 640, 672, 712, 761, 794, 828, 881, 978, 1008, 1044, 1078, 1119, 1156, 1204, 1224, 1266, 1314, 1348, 1392, 1419, 1454, 1529, 1562, 1597, 1625, 1654, 1678, 1749, 1791, 1824, 1883, 1922, 2004, 2040, 2077, 2109, 2141, 2204, 2236, 2276, 2301, 2338], '317,': [165, 196], '5Claudin-19': [167], 'mediates': [168, 382], 'the': [169, 174, 303, 359, 362, 388, 417, 422, 493, 538, 558, 585, 589, 773, 801, 805, 837, 859, 954, 1018, 1025, 1057, 1090, 1211, 1231, 1249, 1323, 1355, 1536, 1581, 1930, 2087, 2250], 'effects': [170], 'NO': [172], 'paracellular': [175, 259], 'pathway': [176, 1606, 1984], 'thick': [178, 263, 390, 590], 'ascending': [179, 264, 391, 591, 1640, 1760], 'limbsCasandra': [180], 'Monzon': [182], 'Jeffrey': [184, 280, 396], 'Garvin31': [186], 'July': [187, 315, 822, 1712, 1998, 2230], '2Concurrent': [198], 'absorption': [199, 1636, 2085], 'secretion': [201, 208, 719, 857, 1858], 'airway': [203], 'surface': [204], 'liquids': [205], 'bicarbonate': [207], 'bronchiolesA.': [211], 'K.': [212, 335, 463, 501, 1140, 1141, 1299, 1300, 1373, 1374], 'Shamsuddin': [214], 'Paul': [216], 'Quinton10': [218], 'May': [219, 249, 634, 2071, 2295], 'Physiology-Lung': [225], 'Cellular': [226], 'Molecular': [228], '316,': [231], '5Role': [233], 'Coronary': [235, 246], 'Myogenic': [236], 'Response': [237], 'Pressure-Flow': [239], 'Autoregulation': [240], 'Swine:': [242], 'A': [243], 'Meta-Analysis': [244], 'With': [245], 'Flow': [247], 'Modeling23': [248], '2018': [250], 'Frontiers': [252], '9Nitric': [256], 'oxide': [257, 385], 'reduces': [258], 'resistance': [260, 1321, 2248], 'rat': [262, 330, 389, 452, 1474, 1541, 1734, 1860, 2118], 'limbs': [265, 456], 'by': [266, 487, 612, 779, 811, 960, 1024, 1236, 1246, 1332, 1433, 1511, 1637, 1802, 1945, 1978, 2359], 'increasing': [267], 'Na+': [268, 2177, 2181], 'Cl−': [270], 'permeabilitiesCasandra': [271], 'Monzon,': [273], 'Rossana': [274], 'Occhipinti,': [275], 'Omar': [276], 'P.': [277, 1865, 1871, 2325], 'Pignataro,': [278], 'Garvin1': [282], '2017': [284], '312,': [292], '650': [294], 'Years': [295], 'renal': [297, 366, 780, 812, 889, 935, 989, 1028, 1100, 1134, 1214, 1284, 1367, 1438, 1949, 2056], 'physiology': [298], 'one': [300], 'man': [301], 'perfused': [304, 450, 1689, 1947], 'tubule:': [305, 2218], 'Maurice': [306], 'B.': [307, 313], 'BurgKirk': [308], 'Hamilton': [310], 'Antoni': [312], 'Moore21': [314], '2016': [316], '311,': [324], '2Isolation': [326], 'perfusion': [328], 'inner': [331, 453, 1861, 2088], 'medullary': [332, 454, 1862, 2089], 'vasa': [333], 'rectaKristen': [334], 'Evans,': [336, 464, 1142, 1301, 1375], 'Michele': [338, 460], 'Nawata,': [339, 461], 'Thomas': [341, 469], 'Pannabecker15': [343], 'August': [344, 513, 972, 1002, 1260, 1523, 1672, 1818, 2135], '2015': [345], '309,': [353], '4Resolving': [355], 'an': [356, 411, 1461], '80-yr-old': [357], 'controversy:': [358], 'beginning': [360], 'modern': [363], 'era': [364], 'physiologyRex': [367], 'Jamison1': [369], 'December': [370, 566, 1413, 1591, 1964], '2014': [371, 400, 433, 473], 'Advances': [373, 547], 'Education,': [376, 550], '38,': [378], '4TRPV4': [380], 'activation': [381], 'flow-induced': [383], 'nitric': [384], 'production': [386], 'limbPablo': [392, 592], 'D.': [393, 507, 593, 749, 1186, 1295, 1585, 1958], 'Cabral,': [394, 594], 'Garvin15': [398], 'September': [399, 598, 1486, 1619, 1648], '307,': [408], '6Even': [410], 'old': [412], 'technique': [413], 'is': [414, 1328, 1431], 'suitable': [415], 'molecular': [418], 'world': [419], 'science:': [421], 'everted': [423], 'sac': [424], 'preparation': [425], 'turns': [426], '60': [427], 'years': [428], 'oldKirk': [429], 'Hamilton15': [431], '306,': [441, 481], '8Transepithelial': [443], 'water': [444, 582, 1684, 2084], 'urea': [446, 1834], 'permeabilities': [447], 'isolated': [449, 1098, 1132, 1365, 1499, 1946], 'Munich-Wistar': [451], 'thin': [455, 1759, 2119], "Henle's": [458, 1763], 'loopC.': [459], 'Kristen': [462], 'William': [465, 2132], 'H.': [466, 1070, 1105, 1108, 1144, 1148, 1196, 1297, 1303, 1380, 1384, 1911, 2129, 2133], 'Dantzler,': [467, 1109, 1304], 'Pannabecker1': [471], 'January': [472, 788, 1072, 1386, 1556, 1935, 2198], '1Endothelin-1': [483], 'inhibits': [484], 'sodium': [485, 1900], 'reabsorption': [486, 778, 810, 959, 1023, 1245, 1510, 1800], 'ETA': [488], 'ETB': [490], 'receptors': [491], 'mouse': [494, 1638, 1690], 'ductI.': [497], 'Jeanette': [498, 733, 1990], 'Lynch,': [499, 734, 1991], 'Amanda': [500], 'Welch,': [502], 'Donald': [503, 2193], 'E.': [504, 743, 1178, 1377, 2330], 'Kohan,': [505], 'Brian': [506, 748], 'Cain,': [508, 750], 'Charles': [510, 752, 1815, 1995], 'S.': [511, 753, 1104, 1143, 1379, 1706, 1816, 1996, 2327], 'Wingo15': [512], '2013': [514, 545], '305,': [522], '4Recognition': [524], 'Society': [528], 'members': [529], 'whose': [530], 'research': [531], 'publications': [532], 'had': [533], 'significant': [535], 'impact': [536], 'discipline': [539], 'physiologyCharles': [541], 'Tipton1': [543], 'March': [544, 666, 755, 1038, 1743, 1785, 1916], '37,': [552], '1Systems': [554], 'biology': [555], 'physiology:': [557], 'vasopressin': [559, 2247], 'signaling': [560], 'network': [561], 'kidneyMark': [563], 'Knepper1': [565, 2269], '2012': [567, 599, 635], '303,': [575, 607], '11Membrane-associated': [577], 'aquaporin-1': [578], 'facilitates': [579], 'osmotically': [580], 'driven': [581], 'flux': [583], 'across': [584, 1686], 'basolateral': [586, 1277, 1434, 1503, 1506, 1982, 2150], 'membrane': [587, 2151], 'Marcela': [596], 'Herrera1': [597], '5Regulation': [609], 'pendrin': [611, 1539], 'cAMP:': [613], 'possible': [614], 'involvement': [615], 'β-adrenergic-dependent': [617], 'NaCl': [618, 1756], 'retentionAnie': [619], 'Azroyan,': [620], 'Luciana': [621], 'Morla,': [622], 'Gilles': [623], 'Crambert,': [624], 'Kamel': [625], 'Laghmani,': [626], 'Sureshkrishna': [627], 'Ramakrishnan,': [628], 'Aurélie': [629], 'Edwards,': [630], 'Alain': [632], 'Doucet1': [633], '302,': [643], '9Genomic': [645], 'nongenomic': [647, 679], 'stimulatory': [648], 'effect': [649, 682], 'aldosterone': [651, 684], 'H+-ATPase': [653], 'proximal': [655, 689, 781, 813, 963, 1029, 1101, 1135, 1174, 1283, 1368, 1402, 1439, 1476, 1514, 1583, 1666, 1832, 1950, 2016, 2148, 2217, 2284], 'S3': [656, 690, 1577], 'segmentsD.': [657], 'Leite-Dellova,': [660, 698], 'G.': [661, 701, 1955, 2264], 'Malnic,': [662, 702], 'Mello-Aires1': [665, 705], '2011': [667], '300,': [675], '3Genomic': [677], 'dose-dependent': [680], 'biphasic': [681], 'Na+/H+': [686, 1233], 'exchanger': [687, 1234, 1472], 'segment:': [691], 'role': [692, 729, 2219, 2245], 'cytosolic': [694], 'calciumD.': [695], 'Oliveira-Souza,': [700], '2008': [707, 756, 789], '295,': [715], '5Impaired': [717], 'acid': [718, 937, 2115], 'intercalated': [724], 'H-K-ATPase-deficient': [727], 'mice:': [728], 'HKα': [731], 'isoformsI.': [732], 'Alicia': [735], 'Rudin,': [736], 'Shen-Ling': [737, 1812, 1992], 'Xia,': [738, 1813, 1993], 'R.': [740, 913, 2032, 2097, 2261], 'Stow,': [741], 'Gary': [742, 1907], 'Shull,': [744], 'I.': [745, 1642, 1697, 1989], 'David': [746, 1910], 'Weiner,': [747], 'Wingo1': [754, 1817, 1997], '294,': [764, 797], '3Role': [766], 'endogenously': [768], 'secreted': [769], 'angiotensin': [770, 1015], 'II': [771, 1016], 'CO2-induced': [774, 806, 955], 'stimulation': [775, 807, 956], 'HCO3': [777], 'tubulesYuehan': [782, 814, 964], 'Zhou,': [783, 815, 965, 1031, 1443, 1518, 1809, 1988], 'Walter': [785, 819, 969, 1035, 1445, 1520], 'F.': [786, 820, 970, 1036, 1446, 1521, 1710], 'Boron1': [787, 821, 971, 1037, 1447, 1522], '1Role': [799], 'AT1A': [802], 'receptor': [803, 1398, 1631], 'HCO3−': [809, 958, 1022], 'Patrice': [816, 966, 1032], 'Bouyer,': [817, 967, 1033, 1441], '2007': [823, 843, 876], '293,': [831], '1Cystic': [833], 'Fibrosis:': [834], 'Lessons': [835], 'Sweat': [838], 'GlandPaul': [839], 'Quinton1': [841], '22,': [847], '3TRPV4': [849], 'as': [850], 'sensor': [853], 'flow-dependent': [855], 'K+': [856, 2183], 'ductJunichi': [862], 'Taniguchi,': [863], 'Shuichi': [864], 'Tsuruoka,': [865], 'Atsuko': [866], 'Mizuno,': [867], 'Jun-ichi': [868], 'Sato,': [869], 'Akio': [870], 'Fujimura,': [871], 'Makoto': [873], 'Suzuki1': [874], 'February': [875, 1342], '292,': [884], '2Impaired': [886], 'intestinal': [887, 933], 'glucose': [890], 'transport': [891, 938, 1096, 1130, 1171, 1568, 1660, 1757, 1944], 'PDK-1': [893], 'hypomorphic': [894, 941], 'miceFerruh': [895], 'Artunc*,': [896], 'Rexhep': [897], 'Rexhepaj*,': [898], 'Harald': [899, 2062], 'Völkl*,': [900, 2063], 'Florian': [901, 916], 'Grahammer,': [902], 'Remy,': [904], 'Diana': [905], 'Sandulache,': [906], 'Omaima': [907], 'Nasir,': [908], 'Carsten': [909], 'Wagner,': [911], 'Dario': [912], 'Alessi,': [914], 'Lang1': [917], '2006': [919, 973, 1003, 1039, 1073], 'Physiology-Regulatory,': [924, 1848, 2168], 'Integrative': [925, 1849, 2169], 'Comparative': [927, 1851, 2171], '291,': [930, 981, 1011], '5Reduced': [932], 'amino': [936], 'PDK1': [940], 'miceThe': [942], 'FASEB': [943], 'Journal,': [944], '20,': [946], '13Role': [948], 'tyrosine': [951, 1085], 'kinase': [952, 1086], 'S2': [962, 1027, 1513], '2Quantitative': [983], 'imaging': [984], 'basic': [986], 'functions': [987], '(patho)physiologyJung': [990], 'Julie': [991], 'Kang,': [992], 'Ildiko': [993], 'Toma,': [994], 'Arnold': [995], 'Sipos,': [996], 'Fiona': [997], 'McCulloch,': [998], 'Janos': [1000], 'Peti-Peterdi1': [1001], '2Effects': [1013], 'CO2': [1019, 1435, 1507, 1797, 1979], 'dependence': [1020], 'tubuleYuehan': [1030], '290,': [1047, 1081], '3The': [1049], 'use': [1050], 'mammalian': [1052], 'slices': [1055], 'tubule': [1060, 1327, 1403, 1833, 1891, 2018, 2149, 2286], 'secretion:': [1061], 'pioneering': [1063], 'step': [1064], 'toward': [1065], 'understanding': [1066], 'organic': [1067, 1169, 1278], 'anion': [1068, 1279], 'transportWilliam': [1069], 'Dantzler1': [1071, 1149, 1385, 2134], '1Involvement': [1083], 'PI3K': [1088], 'regulation': [1091, 1125, 1399, 1632], 'OAT3-mediated': [1093, 1127], 'estrone': [1094, 1128], 'sulfate': [1095, 1129], 'tubulesS.': [1102, 1136], 'Soodvilai,': [1103, 1137], 'Wright,': [1106, 1145, 1381], 'V.': [1111, 1138, 1371, 1908], 'Chatsudthipong1': [1112], '2005': [1114], '289,': [1122], '5Acute': [1124], 'Chatsudthipong,': [1139, 1191, 1372], '2004': [1151, 1199, 1219, 1261, 1309, 1343, 1387], '287,': [1159, 1207, 1227, 1269], '5Relative': [1161], 'contribution': [1162], 'OAT': [1164], 'OCT': [1166], 'transporters': [1167], 'electrolyte': [1170, 1244], 'tubuleXiaohong': [1175], 'Zhang,': [1176], 'Carlotta': [1177], 'Groves,': [1179, 1378], 'Andrew': [1180], 'Bahn,': [1181], 'Wendy': [1182], 'Barendt,': [1184], 'Marcos': [1185], 'Prado,': [1187], 'Matthias': [1188], 'Rödiger,': [1189], 'Varanuj': [1190], 'Gerhard': [1192, 2196], 'Burckhardt,': [1193], 'Stephen': [1195], 'Wright1': [1197], '5Micropuncture:': [1209], 'unlocking': [1210], 'secrets': [1212], 'functionJeff': [1215], 'Sands1': [1217], '5Activation': [1229], 'apical': [1232, 1462, 1537, 2180], 'NHE3': [1235], 'formate:': [1237], 'basis': [1239], 'enhanced': [1241], 'fluid': [1242, 1857], 'formate': [1247], 'kidneySnezana': [1250], 'Petrovic,': [1251, 1478, 1548], 'Sharon': [1252], 'Barone,': [1253], 'Alan': [1254], 'Weinstein,': [1256], 'Manoocher': [1258, 1484, 1554], 'Soleimani1': [1259, 1485, 1555], '2Action': [1271], 'EGF': [1273], 'PGE2': [1275], 'uptake': [1280], 'tubules': [1285], 'hOAT1': [1287], 'expressed': [1288], 'epithelial': [1292], 'cellsC.': [1293], 'Sauvant,': [1294], 'Hesse,': [1296], 'Holzinger,': [1298], 'Gekle1': [1307], '286,': [1317, 1351, 1395], '4Antidiuretic': [1319], 'hormone': [1320], 'neonatal': [1324, 1662], 'mediated': [1329, 1801], 'part': [1331], 'elevated': [1333], 'phosphodiesterase': [1334], 'activityRaymond': [1335], 'Quigley,': [1336, 1668, 1836, 2021, 2158, 2291], 'Sumana': [1337], 'Chakravarty,': [1338], 'Michel': [1340, 1670, 1840, 2022, 2160, 2293], 'Baum1': [1341, 1671, 1841, 2161, 2294], '2Interaction': [1353], 'metal': [1356], 'chelator': [1357], 'DMPS': [1358], 'with': [1359], 'OAT1': [1360], 'OAT3': [1362], 'intact': [1364], 'tubulesA.': [1369], 'Lungkaphin,': [1370], '1Calcium-sensing': [1397], 'PTH-inhibitable': [1401], 'phosphate': [1404], 'transportJianming': [1405], 'Ba,': [1406], 'Dennis': [1407], 'Brown,': [1408], 'Peter': [1410, 1645], 'Friedman1': [1412, 1647], '2003': [1414, 1449, 1487, 1524, 1557], '285,': [1422, 1457, 1495, 1532], '6An': [1424], 'increase': [1425], 'intracellular': [1427, 2213], 'calcium': [1428, 1635], 'concentration': [1429], 'that': [1430], 'induced': [1432], 'tubulePatrice': [1440], 'Yuehan': [1442, 1517], 'October': [1448, 2332], '4Identification': [1459], '\\batchmode': [1463], '\\documentclass[fleqn,10pt,legalpaper]{article}': [1464], '\\usepackage{amssymb}': [1465], '\\usepackage{amsfonts}': [1466], '\\usepackage{amsmath}': [1467], '\\pagestyle{empty}': [1468], '\\begin{document}': [1469], '\\(\\mathrm{Cl}^{-}{/}\\mathrm{HCO}_{3}^{-}\\)': [1470], '\\end{document}': [1471], 'tubuleSnezana': [1477], 'Liyun': [1479, 1551], 'Ma,': [1480, 1552], 'Zhaohui': [1481, 1549], 'Wang,': [1482, 1550], '3Effect': [1497], 'removal': [1500], 'either': [1502], 'HCO3-': [1504, 1509], 'or': [1505, 1688], 'tubuleJinhua': [1515], 'Zhao,': [1516], '2Regulation': [1534], 'Cl−/HCO3−exchanger': [1538], 'metabolic': [1546], 'acidosisSnezana': [1547], '284,': [1565], '1Transepithelial': [1567], 'metabolism': [1570], 'glycine': [1572], 'S1,': [1574], 'S2,': [1575], 'cell': [1578], 'types': [1579], 'tubuleLisa': [1584], 'Parks,': [1586], 'Delon': [1588], 'Barfuss1': [1590], '2002': [1592, 1620, 1649, 1673, 1713, 1744, 1786], '283,': [1600, 1628, 1657, 1681, 1721], '6Leucokinin': [1602], 'activates': [1603], 'Ca2+-dependent': [1604], 'signal': [1605], 'principal': [1608], 'Aedes': [1611], 'aegyptiMalpighian': [1612], 'tubulesMing-Jiun': [1613], 'Yu,': [1614], 'Klaus': [1616], 'Beyenbach1': [1618], '3Calcium-sensing': [1630], 'PTH-dependent': [1634], 'limbsHiroki': [1641], 'Motoyama,': [1643], '3Water': [1659], 'adult': [1664], 'tubulesRaymond': [1667], '2Channel-mediated': [1683], 'movement': [1685], 'enclosed': [1687], 'intrahepatic': [1691], 'bile': [1692], 'unitsAi-Yu': [1694], 'Gong,': [1695], 'Anatoly': [1696], 'Masyuk,': [1698], 'Patrick': [1699], 'Splinter,': [1701], 'Robert': [1702], 'Huebert,': [1704], 'Pamela': [1705], 'Tietz,': [1707], 'Nicholas': [1709], 'LaRusso1': [1711], '1Segmental': [1723], 'localization': [1724], 'mRNAs': [1726], 'encoding': [1727], 'Na+-K+-ATPase': [1728], 'α1-': [1729], 'β1-subunits': [1731], 'diabetic': [1733], 'kidneys': [1735], 'using': [1736], 'RT-PCRP.': [1737], 'Scherzer,': [1738], 'Popovtzer1': [1742], '282,': [1752, 1794], '3Analysis': [1754], 'limb': [1761, 2120], 'loop': [1764, 2124], 'CLC-K1': [1766], 'null': [1767], 'miceWen': [1768], 'Liu,': [1769], 'Tetsuji': [1770], 'Morimoto,': [1771], 'Yoshiaki': [1772], 'Kondo,': [1773], 'Kazuie': [1774], 'Iinuma,': [1775], 'Shinichi': [1776], 'Uchida,': [1777], 'Sei': [1778], 'Sasaki,': [1779], 'Fumiaki': [1780], 'Marumo,': [1781], 'Masashi': [1783], 'Imai1': [1784], '3Increased': [1796], 'stimulates': [1798], 'K/Rb': [1799], 'H-K-ATPase': [1803], 'CCD': [1805], 'potassium-restricted': [1807], 'rabbitXiaoming': [1808], 'Suguru': [1810], 'Nakamura,': [1811], '2001': [1819, 1843, 1878, 1917, 1936], '281,': [1827], '2Ontogeny': [1829], 'permeabilityRaymond': [1835], 'Amber': [1837], 'Lisec,': [1838], '280,': [1854, 1886, 1925], '6cAMP-dependent': [1856], 'ductsDarren': [1864], 'Wallace,': [1866], 'Lorraine': [1867], 'Rome,': [1869], 'Lawrence': [1870], 'Sullivan,': [1872], 'Jared': [1874], 'J.': [1875, 2031, 2101, 2258], 'Grantham1': [1876], '6The': [1888], 'distal': [1889], 'convoluted': [1890], 'does': [1895], 'not': [1896], 'express': [1897], 'functional': [1899], 'channelHeino': [1901], 'Velázquez,': [1902], 'Teresa': [1903], 'Silva,': [1904], 'Eleanor': [1905], 'Andújar,': [1906], 'Desir,': [1909], 'Ellison,': [1912], 'Rainer': [1914], 'Greger1': [1915], '3Potassium': [1927], 'Transport': [1928], 'Mammalian': [1931], 'Collecting': [1932], 'DuctShigeaki': [1933], 'Muto1': [1934], '81,': [1941], '1Riboflavin': [1943], 'tubulesNorimoto': [1951], 'Yanagawa,': [1952], 'Remi': [1953], 'N.': [1954, 2224], 'Shih,': [1956], 'Oak': [1957], 'Jo,': [1959], 'Hamid': [1961], 'Said1': [1963], '2000': [1965, 1999, 2035, 2072], '279,': [1973, 2007], '6Activation': [1975], 'H+-K+-ATPase': [1977], 'requires': [1980], 'Ba2+-sensitive': [1983], 'during': [1985, 2125], 'K': [1986], 'restrictionXiaoming': [1987], '1Effects': [2009], '20-HETE': [2011], '19(S)-HETE': [2013], 'straight': [2017, 2285], 'volume': [2019], 'transportRaymond': [2020], 'Baum,': [2023], 'Komandla': [2024], 'Malla': [2025], 'Reddy,': [2026], 'James': [2027], 'Griener,': [2029], 'Falck1': [2033], '278,': [2043, 2080], '6Luminal': [2045], 'contraluminal': [2047], 'action': [2048], '1–34': [2050], '3–34': [2052], 'PTH': [2053], 'peptides': [2054], 'type': [2057], 'IIa': [2058], 'Na-Pi': [2059], 'cotransporterMartin': [2060], 'Traebert*,': [2061], 'Jürg': [2064], 'Biber,': [2065], 'Heini': [2066], 'Murer,': [2067], 'Brigitte': [2069], 'Kaissling1': [2070], '5Thiazide': [2082], 'induces': [2083], 'normal': [2093], 'Brattleboro': [2095], 'ratsKátia': [2096], 'César,': [2098], 'Antonio': [2100], 'Magaldi1': [2102], '1999': [2104, 2136, 2163, 2199], '277,': [2112, 2144], '5Amino': [2114], 'fluxes': [2116], 'Henle’s': [2123], 'vitro': [2127], 'microperfusionOlga': [2128], 'Brokl,': [2130], '2Neonatal': [2146], 'Na+/H+antiporter': [2152], 'Cl−/base': [2154], 'exchangeMehul': [2155, 2288], 'Shah,': [2156, 2289], 'Raymond': [2157, 2290], '276,': [2174, 2207], '6Basolateral': [2176], 'pump': [2178], 'modulates': [2179], 'conductances': [2184], 'ductsShigeaki': [2189], 'Muto,': [2190], 'Yasushi': [2191], 'Asano,': [2192], 'Seldin,': [2194], 'Giebisch1': [2197], '1Effect': [2209], 'norepinephrine': [2211], 'pH': [2214], 'Na+-(HCO3−)ncotransportSolange': [2221], 'Abdulnour-Nakhoul,': [2222], 'Raja': [2223], 'Khuri†,': [2225], 'Nazih': [2227], 'Nakhoul1': [2229], '1998': [2231, 2271, 2296], '275,': [2239], '1Escape': [2241], 'vasopressin-induced': [2243], 'antidiuresis:': [2244], 'ductCarolyn': [2252], 'Ecelbarger,': [2254], 'Chung-Lin': [2255], 'Chou,': [2256], 'Alanna': [2257], 'Lee,': [2259], 'Susan': [2260], 'DiGiovanni,': [2262], 'Joseph': [2263], 'Verbalis,': [2265], 'Mark': [2267], '274,': [2279, 2304], '6Maturation': [2281], 'chloride/base': [2287], '5A': [2306], 'simplified': [2307], 'large': [2312], 'numbers': [2313], 'segmentsJ.': [2317], 'Schafer,': [2319], 'Watkins,': [2322], 'Li,': [2324], 'Herter,': [2326], 'Haxelmans,': [2328], 'Schlatter1': [2331], '1997': [2333], '273,': [2341], '4': [2343], 'More': [2344], 'this': [2346], 'issue': [2347], '>': [2348], 'Volume': [2349], '210Issue': [2350], '6June': [2351], '1966Pages': [2352], '1293-1298': [2353], 'Copyright': [2354], '&': [2355], 'PermissionsCopyright': [2356], '©': [2357], '1966': [2358, 2367, 2373], 'Societyhttps://doi.org/10.1152/ajplegacy.1966.210.6.1293PubMed5923067History': [2362], 'Published': [2363, 2368], 'online': [2364], '1': [2365, 2371], 'print': [2370], 'Metrics': [2374], 'Downloaded': [2375], '262': [2376], 'times': [2377]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2410203954', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 15}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-12-13T17:52:34.075160', 'created_date': '2016-06-24'}