Title: [Basaloid squamous cell carcinoma: clinical pathological and immunohistochemical study].
Abstract: To investigate the clinicopathological and immunohistochemical characteristics of basaloid squamous cell carcinoma of oral cavity.Routine HE staining and immunohistochemical staining.Basaloid squamous cell carcinoma accounted for 1% of oral squamous cell carcinoma and was more common in male. It could be found at anysite of oral mucosa. The tumor was composed of basaloid cells and squamous cells. Basaloid cell, the main tumor cell, arranged in sheets and nests. Mitosis and comedoform necrosis was often seen. Adjacent oral epithelium often exhibited dysplasia. The tumor cells were cytokeratin positive, S-100 negative; PCNA index was high; 50% cases were p53 positive.Oral basaloid squamous cell carcinoma was a higher grade malignant tumor as compared with usual squamous cell carcinoma and should be paid great attention both in treatment and in pathological diagnosis.
Publication Year: 1998
Publication Date: 1998-09-01
Language: en
Type: article
Indexed In: ['pubmed']
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