Title: Coexistence of cognitive impairment and depression in geriatric outpatients
Abstract: Back to table of contents Previous article Next article No AccessCoexistence of cognitive impairment and depression in geriatric outpatientsPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.139.5.623AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractThe authors diagnosed depression in 20 (23%) of 88 cognitively impaired geriatric outpatients. Three (20%) of these patients had depression only, and 17 (85%) had depression superimposed on an underlying dementia. The rate of coexisting depression decreased significantly with greater severity of the cognitive impairment: 9 (33%) of 27 mildly impaired patients were depressed, compared with 8 (23%) of 35 moderately impaired and 3 (12%) of 26 severely impaired patients. There was a nonsignificant trend for cognitively impaired women to be more likely to be depressed than for similarly impaired men. The authors conclude that although depression must be differentiated from dementia, it is equally important to consider the possibility that the diagnoses coexist. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byEmotional and Neuropsychiatric Disorders Associated with Alzheimer's Disease10 January 2022 | Neurotherapeutics, Vol. 19, No. 1Functional cognitive disorders: a systematic reviewThe Lancet Psychiatry, Vol. 7, No. 2Psychological Medicine, Vol. 49, No. 5Applied Neuropsychology: Adult, Vol. 24, No. 1Depressive Disorders: Major Depressive Disorder and Persistent Depressive Disorder20 February 2015The American Journal of Geriatric Psychiatry, Vol. 22, No. 1Geriatrics & Gerontology International, Vol. 13, No. 2PLoS ONE, Vol. 8, No. 11International Journal of Geriatric Psychiatry, Vol. 26, No. 10Psychiatry Investigation, Vol. 6, No. 4The influence of lifetime depression on self-reported memory and cognitive problems: Results from the National Comorbidity Survey–Replication7 April 2008 | Aging & Mental Health, Vol. 12, No. 2Treatment of Cognitive Decline and Psychiatric Disturbances Associated With Alzheimer's Dementia30 June 2016 | Journal of Pharmacy Practice, Vol. 20, No. 1Psychogeriatrics, Vol. 6, No. 4Biological Psychiatry, Vol. 58, No. 4The American Journal of Geriatric Psychiatry, Vol. 13, No. 6Dementia and Geriatric Cognitive Disorders, Vol. 19, No. 1Clinical Psychology & Psychotherapy, Vol. 10, No. 3The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Vol. 58, No. 3International Journal of Geriatric Psychiatry, Vol. 17, No. 5Geriatric Depression30 June 2016 | Journal of Pharmacy Practice, Vol. 14, No. 6International Journal of Geriatric Psychiatry, Vol. 16, No. 1International Journal of Geriatric Psychiatry, Vol. 16, No. 10Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 28, No. S1Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 28, No. S1The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Vol. 56, No. 8The Neurologist, Vol. 7, No. 4Psychosomatics, Vol. 42, No. 1Chancen und Risiken von Patientenverfügungen bei dementiellen StörungenZeitschrift für Gerontopsychologie & -psychiatrie, Vol. 13, No. 1, Vol. 3ReferencesEpidemiologia e Psichiatria Sociale, Vol. 9, No. 2Journal of the American Geriatrics Society, Vol. 48, No. 5Health Care Utilization by Older Patients With Coexisting Dementia and DepressionHelen C. Kales, M.D., Frederic C. Blow, Ph.D., Laurel A. Copeland, M.P.H., Raymond C. Bingham, Ph.D., Ericka E. Kammerer, B.A., M.B.A., and Alan M. Mellow, M.D., Ph.D.1 April 1999 | American Journal of Psychiatry, Vol. 156, No. 4Organic Brain Disease in Psychogeriatric Patients: Impact of Symptoms and Screening Methods on the Diagnostic Process29 June 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 12, No. 1Aging Clinical and Experimental Research, Vol. 11, No. 2Current Psychiatry Reports, Vol. 1, No. 1Journal of Affective Disorders, Vol. 52, No. 1-3Reviews in the Neurosciences, Vol. 10, No. 2Assessment and Management of Medically Ill Patients who Refuse Life-Prolonging Treatments: Two Case Reports and Proposed Guidelines8 April 2019 | Journal of Palliative Care, Vol. 14, No. 1Biological Psychiatry, Vol. 43, No. 3Aging & Mental Health, Vol. 2, No. 4Effects of Alzheimer's disease severity on cerebrospinal fluid norepinephrine concentration1 April 2006 | American Journal of Psychiatry, Vol. 154, No. 1Neuropsychology Review, Vol. 7, No. 1Clinical Psychology Review, Vol. 17, No. 8Journal of Clinical and Experimental Neuropsychology, Vol. 19, No. 5Premorbid History of Major Depression and the Depressive Syndrome of Alzheimer's DiseaseThe American Journal of Geriatric Psychiatry, Vol. 4, No. 1Confirmation of an association between family history of affective disorder and the depressive syndrome in Alzheimer's disease1 April 2006 | American Journal of Psychiatry, Vol. 153, No. 10International Journal of Geriatric Psychiatry, Vol. 11, No. 6, Vol. 47Journal of Affective Disorders, Vol. 36, No. 3-4Archives of Gerontology and Geriatrics, Vol. 22Depresión y deterioro cognitivo en los ancianos: un estudio multicéntrico12 May 2020 | European psychiatry (Ed. Española), Vol. 2, No. 4Depressive Symptoms in Alzheimer's Disease and Multi-infarct Dementia29 June 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 8, No. 2Prevalence and correlates of dysthymia and major depression among patients with Alzheimer's disease1 April 2006 | American Journal of Psychiatry, Vol. 152, No. 1International Journal of Geriatric Psychiatry, Vol. 10, No. 5International Journal of Geriatric Psychiatry, Vol. 10, No. 6Behavioural Brain Research, Vol. 67, No. 2Depression and cognitive impairment in the elderly: a multicentre study16 April 2020 | European Psychiatry, Vol. 10, No. 2Reviews in Clinical Gerontology, Vol. 5, No. 1Aging, Neuropsychology, and Cognition, Vol. 2, No. 3The Clinical Neuropsychologist, Vol. 9, No. 2Journal of the American Geriatrics Society, Vol. 43, No. 5Journal of the American Geriatrics Society, Vol. 43, No. 2Clinical Neurology and Neurosurgery, Vol. 96, No. 2Clinics in Geriatric Medicine, Vol. 10, No. 2Clinics in Geriatric Medicine, Vol. 10, No. 2Journal of the American Geriatrics Society, Vol. 42, No. 2British Journal of Psychiatry, Vol. 164, No. 3Les manifestations psychiatriques dans la démence: perspective phénoménologique1 December 1993 | The Canadian Journal of Psychiatry, Vol. 38, No. 10Depression versus Dementia1 March 1993 | The Canadian Journal of Psychiatry, Vol. 38, No. 2Journal of Neural Transmission, Vol. 91, No. 2-3Biological Psychiatry, Vol. 33, No. 4Electroencephalography and Clinical Neurophysiology, Vol. 86, No. 4General Hospital Psychiatry, Vol. 15, No. 6Journal of Affective Disorders, Vol. 29, No. 1Psychiatric Clinics of North America, Vol. 16, No. 4Journal of Clinical and Experimental Neuropsychology, Vol. 15, No. 2Journal of Clinical and Experimental Neuropsychology, Vol. 15, No. 1Journal of the American Geriatrics Society, Vol. 41, No. 3Cognitive Changes Associated With Depression (Pseudodementia)2 September 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 6, No. 1Nordic Journal of Psychiatry, Vol. 47, No. sup28Nordic Journal of Psychiatry, Vol. 47, No. sup30NeuropsychiatryMixed neurologic and psychiatric disorders: Pharmacological issuesComprehensive Psychiatry, Vol. 33, No. 5Brain computed tomography findings in geriatric depression and primary degenerative dementiaBiological Psychiatry, Vol. 31, No. 6International Journal of Geriatric Psychiatry, Vol. 7, No. 5International Journal of Geriatric Psychiatry, Vol. 7, No. 7Neurochemical Research, Vol. 17, No. 9European Archives of Psychiatry and Clinical Neuroscience, Vol. 242, No. 2-3Psychopharmacology, Vol. 106, No. S1Current Therapeutic Research, Vol. 52, No. 6Clinics in Geriatric Medicine, Vol. 8, No. 2Clinics in Geriatric Medicine, Vol. 8, No. 2Clinics in Geriatric Medicine, Vol. 8, No. 1Psychological Medicine, Vol. 22, No. 1New England Journal of Medicine, Vol. 326, No. 14Journal of Clinical and Experimental Neuropsychology, Vol. 14, No. 4International Journal of Neuroscience, Vol. 64, No. 1-4Criteria for recommending options for the elderly cognitively impaired4 September 2016 | American Journal of Alzheimer's Care and Related Disorders & Research, Vol. 6, No. 4Delusions, hallucinations and depression in Alzheimer's disease: A biological perspective4 September 2016 | American Journal of Alzheimer's Care and Related Disorders & Research, Vol. 6, No. 3International Journal of Geriatric Psychiatry, Vol. 6, No. 6International Journal of Geriatric Psychiatry, Vol. 6, No. 6Psychiatric Clinics of North America, Vol. 14, No. 2Psychological Medicine, Vol. 21, No. 2Psychiatry, Vol. 54, No. 4Journal of the American Geriatrics Society, Vol. 39, No. 3Journal of the American Geriatrics Society, Vol. 39, No. 3Journal of the American Geriatrics Society, Vol. 39, No. 9Depression in Patients with Alzheimer's Disease and Multi-Infarct Dementia2 September 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 4, No. 1Depression in dementia of the Alzheimer type and in multi-infarct dementia1 April 2006 | American Journal of Psychiatry, Vol. 147, No. 11Alzheimer's disease and depression: neuropsychological impairment and progression of the illness1 April 2006 | American Journal of Psychiatry, Vol. 147, No. 7Association between family history of affective disorder and the depressive syndrome of Alzheimer's disease1 April 2006 | American Journal of Psychiatry, Vol. 147, No. 4International Journal of Geriatric Psychiatry, Vol. 5, No. 2International Journal of Geriatric Psychiatry, Vol. 5, No. 3International Journal of Geriatric Psychiatry, Vol. 5, No. 3International Journal of Geriatric Psychiatry, Vol. 5, No. 3, Vol. 282, Vol. 1Journal of General Internal Medicine, Vol. 5, No. 5Journal of General Internal Medicine, Vol. 5, No. 1Clinical Psychology Review, Vol. 10, No. 5Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 14, No. 5Journal of the American Geriatrics Society, Vol. 38, No. 5Journal of Neurology, Neurosurgery & Psychiatry, Vol. 53, No. 3British Journal of Psychiatry, Vol. 157, No. S9British Journal of Psychiatry, Vol. 157, No. 1Dementia with coexistent major depression1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 11Assess Not Assume: Measuring the Morale of Cognitively Impaired ElderlyJournal of Gerontological Nursing, Vol. 15, No. 11Chronicity and relapse in geriatric depressionBiological Psychiatry, Vol. 26, No. 6Psychopathology of very mild dementia of the Alzheimer type1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 8Overview of depression and psychosis in Alzheimer's disease1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 5HLA Antigens in Depressed, Demented, and Nondemented Elderly2 September 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 2, No. 2Depression and Alzheimer's disease1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 3Double-blind trial of imipramine in Alzheimer's disease patients with and without depression1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 1International Journal of Geriatric Psychiatry, Vol. 4, No. 6Human Psychopharmacology: Clinical and Experimental, Vol. 4, No. 4Electroencephalography and Clinical Neurophysiology, Vol. 72, No. 4Psychological Medicine, Vol. 19, No. 3Australian and New Zealand Journal of Medicine, Vol. 19, No. 5Journal of the American Geriatrics Society, Vol. 37, No. 1Journal of the American Geriatrics Society, Vol. 37, No. 12Acta Psychiatrica Scandinavica, Vol. 80, No. 5Opportunities for Psychotherapy in the Management of Dementia2 September 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 2, No. 1British Journal of Psychiatry, Vol. 155, No. 3Journal of Psychotherapy & The Family, Vol. 5, No. 1-2Overlapping Symptoms of Geriatric Depression and Alzheimer-Type DementiaEugene H. Rubin, Charles F. Zorumski, and William J. Burke1 April 2006 | Psychiatric Services, Vol. 39, No. 10Bedside differentiation of depressive pseudodementia from dementia1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 9Reliability of psychiatric scales in patients with dementia of the Alzheimer type1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 7Depression, Dementia, and Social Supports1 January 1995 | The International Journal of Aging and Human Development, Vol. 26, No. 4Depressive Symptoms in Patients with Primary Degenerative Dementia2 September 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 1, No. 2Endocrine Changes in Alzheimer's DiseaseNeurologic Clinics, Vol. 6, No. 1International Journal of Geriatric Psychiatry, Vol. 3, No. 2Biological Psychiatry, Vol. 23, No. 3Biological Psychiatry, Vol. 24, No. 6Brain Research, Vol. 472, No. 4Brain Research Reviews, Vol. 13, No. 4Psychiatry Research, Vol. 25, No. 3Psychoneuroendocrinology, Vol. 13, No. 4Medical Clinics of North America, Vol. 72, No. 4Psychiatric Clinics of North America, Vol. 11, No. 1Psychiatric Clinics of North America, Vol. 11, No. 1Clinics in Geriatric Medicine, Vol. 4, No. 4Clinics in Geriatric Medicine, Vol. 4, No. 4Endocrinology and Metabolism Clinics of North America, Vol. 17, No. 1Journal of the American Geriatrics Society, Vol. 36, No. 3Journal of the American Geriatrics Society, Vol. 36, No. 1British Journal of Psychiatry, Vol. 152, No. 2Psychiatric Morbidity in Hobart's Dependent Aged26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 21, No. 4Differential Diagnosis of Depressive Pseudodementia and Primary Degenerative DementiaPsychiatric Annals, Vol. 17, No. 11CSF somatostatin in patients with Alzheimer's disease, older depressed patients, and age-matched control subjects1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 10Assessing Dementia. Part I: Difficulties, Definitions and Differential Diagnosis26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 21, No. 2Standardized Assessment of A Dementia Clinic Population4 September 2016 | American Journal of Alzheimer's Care and Related Disorders & Research, Vol. 2, No. 2Frequency and presentation of depressive symptoms in patients with primary degenerative dementia [published erratum appears in Am J Psychiatry 1987 Apr;144(4):542]1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 1Biological Psychiatry, Vol. 22, No. 2Comprehensive Psychiatry, Vol. 28, No. 5Oral Surgery, Oral Medicine, Oral Pathology, Vol. 64, No. 5Psychiatry Research, Vol. 21, No. 2Clinics in Geriatric Medicine, Vol. 3, No. 1Clinical Neuropsychologist, Vol. 1, No. 1Journal of the American Geriatrics Society, Vol. 35, No. 2Journal of the American Geriatrics Society, Vol. 35, No. 6Journal of the American Geriatrics Society, Vol. 35, No. 12Acta Neurologica Scandinavica, Vol. 76, No. 5British Journal of Psychiatry, Vol. 150, No. 4Australian Journal of Human Communication Disorders, Vol. 15, No. 1Psychiatric Residents' Experience and Career Interest in Geriatric Psychiatry: Implications for Training Programs1 December 1986 | The Canadian Journal of Psychiatry, Vol. 31, No. 9Using Electroconvulsive Therapy for Patients With Neurological DiseaseSteven L. Dubovsky1 April 2006 | Psychiatric Services, Vol. 37, No. 8Empirical Study on an Inpatient Psychogeriatric Unit: Biological Treatment in Patients with Depressive Illness1 January 1995 | The International Journal of Psychiatry in Medicine, Vol. 15, No. 2Differential Diagnosis of Dementing IllnessesNeurologic Clinics, Vol. 4, No. 2ALZHEIMER'S DISEASE SYNDROMEJournal of Psychosocial Nursing and Mental Health Services, Vol. 24, No. 5Cortisol and Alzheimer's disease, II: Dexamethasone suppression, dementia severity, and affective symptoms1 April 2006 | American Journal of Psychiatry, Vol. 143, No. 4Cognitive Deficit in the Depressed Elderly: A Review of Some Basic Unresolved Issues26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 20, No. 1Annals of Neurology, Vol. 19, No. 1International Journal of Geriatric Psychiatry, Vol. 1, No. 2New Directions for Mental Health Services, Vol. 1986, No. 29The Italian Journal of Neurological Sciences, Vol. 7, No. 1Journal of General Internal Medicine, Vol. 1, No. 2Journal of Psychiatric Research, Vol. 20, No. 4Psychoneuroendocrinology, Vol. 11, No. 3New England Journal of Medicine, Vol. 314, No. 15Journal of the American Geriatrics Society, Vol. 34, No. 11Journal of the American Geriatrics Society, Vol. 34, No. 3Journal of the American Geriatrics Society, Vol. 34, No. 4Journal of the American Geriatrics Society, Vol. 34, No. 5Journal of the American Geriatrics Society, Vol. 34, No. 1Journal of the American Geriatrics Society, Vol. 34, No. 12The Dexamethasone Suppression Test in Elderly, Non-Depressed Patients with Dementia26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 19, No. 1Consistent reversal of abnormal DSTs after different antidepressant therapies in a patient with dementia1 April 2006 | American Journal of Psychiatry, Vol. 142, No. 1Drug Development Research, Vol. 5, No. 1Psychiatry Research, Vol. 16, No. 4Psychiatry Research, Vol. 16, No. 4Archives of Gerontology and Geriatrics, Vol. 4, No. 4Developmental Neuropsychology, Vol. 1, No. 2Drug Development Research, Vol. 4, No. 5Psychosomatics, Vol. 25, No. 7Neurologic Clinics, Vol. 2, No. 1Psychological Medicine, Vol. 14, No. 1Journal of the American Geriatrics Society, Vol. 32, No. 4Journal of the American Geriatrics Society, Vol. 32, No. 7Journal of the American Geriatrics Society, Vol. 32, No. 2Australian Journal on Ageing, Vol. 3, No. 1British Journal of Psychiatry, Vol. 145, No. 6Dexamethasone Suppression Test in Primary Degenerative DementiaLEON GRUNHAUS, JOHN F. GREDEN, and BERNARD J. CARROLL1 April 2006 | American Journal of Psychiatry, Vol. 140, No. 8Coexistence of Mania and DepressionBURTON V. REIFLER1 April 2006 | American Journal of Psychiatry, Vol. 140, No. 8Dr. Knesevich and Associates ReplyJOHN WILLIAM KNESEVICH, RONALD L. MARTIN, LEONARD BERG, and WARREN DANZIGER1 April 2006 | American Journal of Psychiatry, Vol. 140, No. 8Dexamethasone suppression test in primary degenerative dementia23 January 2015 | American Journal of Psychiatry, Vol. 140, No. 8Coexistence of mania and depression23 January 2015 | American Journal of Psychiatry, Vol. 140, No. 8Psychosomatic Disorders in the Elderly1 February 1983 | The Canadian Journal of Psychiatry, Vol. 28, No. 1Annals of Neurology, Vol. 14, No. 5Psychiatry Research, Vol. 9, No. 4Postgraduate Medicine, Vol. 73, No. 4Journal of the American Geriatrics Society, Vol. 31, No. 12Journal of the American Geriatrics Society, Vol. 31, No. 5Australian Journal on Ageing, Vol. 2, No. 1The Lancet, Vol. 320, No. 8313Journal of the American Geriatrics Society, Vol. 30, No. 10 Volume 139Issue 5 May 1982Pages 623-626 Metrics PDF download History Published online 1 April 2006 Published in print 1 May 1982
Publication Year: 1982
Publication Date: 1982-05-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 367
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot