Title: The treatment of dysmenorrhea with naproxen sodium
Abstract: The efficacy of naproxen sodium (naproxen-Na) ∗ Naproxen-sodium is the sodium salt of a-2-(6′-methoxy-2′ naphthyl)-propionic acid. ∗Naproxen-sodium is the sodium salt of a-2-(6′-methoxy-2′ naphthyl)-propionic acid. in dysmenorrhea has been established in two independent double-blind (placebo-controlled) studies. An initial dose of 550 mg. of naproxen-Na was followed by 275 mg. every six hours for a maximum of five days. Twenty patients were included in Study I (10 treated with naproxen-Na) and 23 patients in Study II (12 treated with naproxen-Na). Each patient received the medication during four dysmenorrheic episodes. Thus, a total of 172 treatment courses could be evaluated. A variety of efficacy criteria were measured: frequency of pill intake, changes in pain intensity, the degree of relief achieved by the medication, and need for additional analgesics. In both studies naproxen-Na was demonstrated to be superior to the placebo treatment with high statistical significance in each of these parameters.
Publication Year: 1977
Publication Date: 1977-04-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 86
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