Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2404105891', 'doi': 'https://doi.org/10.1002/rcm.7574', 'title': '<b>Mass measurement accuracy of the Orbitrap in intact proteome analysis</b>', 'display_name': '<b>Mass measurement accuracy of the Orbitrap in intact proteome analysis</b>', 'publication_year': 2016, 'publication_date': '2016-05-15', 'ids': {'openalex': 'https://openalex.org/W2404105891', 'doi': 'https://doi.org/10.1002/rcm.7574', 'mag': '2404105891', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27197031'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/rcm.7574', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89689683', 'display_name': 'Rapid Communications in Mass Spectrometry', 'issn_l': '0951-4198', 'issn': ['0951-4198', '1097-0231'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050847417', 'display_name': 'Fan Yu', 'orcid': 'https://orcid.org/0000-0002-4978-0023'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Fan Yu', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028024085', 'display_name': 'Houqin Fang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Houqin Fang', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039887185', 'display_name': 'Kaijie Xiao', 'orcid': 'https://orcid.org/0000-0002-3479-6348'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kaijie Xiao', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100351131', 'display_name': 'Yan Liu', 'orcid': 'https://orcid.org/0000-0002-9904-4438'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yan Liu', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033364220', 'display_name': 'Bingbing Xue', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bingbing Xue', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5042231897', 'display_name': 'Zhixin Tian', 'orcid': 'https://orcid.org/0000-0002-2877-8282'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zhixin Tian', 'raw_affiliation_strings': ['Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry and Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092 China', 'institution_ids': ['https://openalex.org/I116953780']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5042231897'], 'corresponding_institution_ids': ['https://openalex.org/I116953780'], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.151, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.555404, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '30', 'issue': '12', 'first_page': '1391', 'last_page': '1397'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12388', 'display_name': 'DNA Barcoding for Food Authentication and Fraud Detection', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10519', 'display_name': 'Mass Spectrometry Techniques with Proteins', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/orbitrap', 'display_name': 'Orbitrap', 'score': 0.96570706}, {'id': 'https://openalex.org/keywords/mass-spectrometry', 'display_name': 'Mass Spectrometry', 'score': 0.565531}, {'id': 'https://openalex.org/keywords/tandem-mass-spectrometry', 'display_name': 'Tandem Mass Spectrometry', 'score': 0.552394}, {'id': 'https://openalex.org/keywords/proteome', 'display_name': 'Proteome', 'score': 0.5137001}, {'id': 'https://openalex.org/keywords/mass', 'display_name': 'Mass', 'score': 0.4514871}], 'concepts': [{'id': 'https://openalex.org/C2780841973', 'wikidata': 'https://www.wikidata.org/wiki/Q2607924', 'display_name': 'Orbitrap', 'level': 3, 'score': 0.96570706}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.8581419}, {'id': 'https://openalex.org/C162356407', 'wikidata': 'https://www.wikidata.org/wiki/Q180809', 'display_name': 'Mass spectrometry', 'level': 2, 'score': 0.7588945}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.67086226}, {'id': 'https://openalex.org/C40325409', 'wikidata': 'https://www.wikidata.org/wiki/Q2360668', 'display_name': 'Mass spectrum', 'level': 3, 'score': 0.5999938}, {'id': 'https://openalex.org/C113196181', 'wikidata': 'https://www.wikidata.org/wiki/Q485223', 'display_name': 'Analytical Chemistry (journal)', 'level': 2, 'score': 0.5940854}, {'id': 'https://openalex.org/C165838908', 'wikidata': 'https://www.wikidata.org/wiki/Q736777', 'display_name': 'Calibration', 'level': 2, 'score': 0.5849599}, {'id': 'https://openalex.org/C31827203', 'wikidata': 'https://www.wikidata.org/wiki/Q874296', 'display_name': 'Tandem mass spectrometry', 'level': 3, 'score': 0.5356592}, {'id': 'https://openalex.org/C104397665', 'wikidata': 'https://www.wikidata.org/wiki/Q860947', 'display_name': 'Proteome', 'level': 2, 'score': 0.5137001}, {'id': 'https://openalex.org/C115139119', 'wikidata': 'https://www.wikidata.org/wiki/Q3850884', 'display_name': 'Mass', 'level': 4, 'score': 0.4514871}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.08586332}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.07337174}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.056849837}], 'mesh': [{'descriptor_ui': 'D056148', 'descriptor_name': 'Chromatography, Reverse-Phase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020543', 'descriptor_name': 'Proteome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D053719', 'descriptor_name': 'Tandem Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007477', 'descriptor_name': 'Ions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/rcm.7574', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89689683', 'display_name': 'Rapid Communications in Mass Spectrometry', 'issn_l': '0951-4198', 'issn': ['0951-4198', '1097-0231'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27197031', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 14, 'referenced_works': ['https://openalex.org/W1982468602', 'https://openalex.org/W2005088298', 'https://openalex.org/W2019732897', 'https://openalex.org/W2027603999', 'https://openalex.org/W2056499061', 'https://openalex.org/W2073229999', 'https://openalex.org/W2077037916', 'https://openalex.org/W2110812878', 'https://openalex.org/W2134749398', 'https://openalex.org/W2138832989', 'https://openalex.org/W2148810638', 'https://openalex.org/W2171192777', 'https://openalex.org/W2320653595', 'https://openalex.org/W2410718960'], 'related_works': ['https://openalex.org/W3093675403', 'https://openalex.org/W2767281251', 'https://openalex.org/W2188446247', 'https://openalex.org/W2103613158', 'https://openalex.org/W2100623735', 'https://openalex.org/W2078598194', 'https://openalex.org/W2012663189', 'https://openalex.org/W1986600441', 'https://openalex.org/W1552121931', 'https://openalex.org/W153919878'], 'abstract_inverted_index': {'Rationale': [0], 'The': [1, 85, 105, 158], 'mass': [2, 8, 27, 48, 57, 75, 103, 117, 153, 160, 202, 216, 231, 250], 'measurement': [3, 217], 'accuracy': [4, 161, 203, 218], '(MMA)': [5], 'of': [6, 39, 61, 119, 155, 162, 200, 210, 219, 222], 'Orbitrap': [7, 31, 74, 224], 'spectrometers': [9], 'is': [10, 41, 252], '1–5': [11, 220], 'ppm': [12, 22, 221, 241], 'according': [13], 'to': [14, 20, 29, 44, 50, 78, 192, 238], 'the': [15, 34, 46, 62, 138, 141, 180, 186, 207, 215, 223, 227, 229, 244, 263], "manufacturer's": [16], 'specification;': [17], 'yet,': [18], 'up': [19], '50': [21], 'has': [23], 'been': [24], 'used': [25], 'as': [26, 177, 179], 'tolerance': [28, 49, 154, 232], 'interpret': [30], 'data': [32], 'in': [33, 184, 258], 'literature.': [35], 'A': [36], 'systematic': [37], 'evaluation': [38], 'MMA': [40, 259], 'thus': [42], 'necessary': [43], 'find': [45], 'optimal': [47, 230], 'be': [51, 193, 239], 'used.': [52], 'Methods': [53], 'Reversed-phase': [54], 'liquid': [55], 'chromatography/tandem': [56], 'spectrometry': [58], '(RPLC/MS/MS)': [59], 'analyses': [60], 'intact': [63], 'E.': [64], 'coli': [65], 'proteome': [66], 'were': [67, 109, 149], 'carried': [68], 'out': [69], 'on': [70], 'a': [71, 79, 102, 152], 'Q': [72], 'Exactive': [73], 'spectrometer': [76], 'coupled': [77], 'Dionex': [80], 'UltiMate': [81], '3000': [82], 'RSLCnano': [83], 'system.': [84], 'analysis': [86], 'included': [87], 'three': [88, 169], 'technical': [89], 'replicates': [90], 'each': [91], 'day': [92], 'and': [93, 123, 130, 134, 146, 165, 173, 196, 246], 'was': [94, 190, 204, 236, 260], 'repeated': [95], 'for': [96, 233, 242], 'six': [97], 'continuous': [98], 'days': [99], 'right': [100], 'after': [101], 'calibration.': [104], 'obtained': [106, 150], 'raw': [107], 'datasets': [108], 'searched': [110], 'using': [111], 'ProteinGoggle': [112], '2.0': [113], 'under': [114], 'four': [115], 'different': [116], 'tolerances': [118], '5,': [120], '10,': [121], '15,': [122], '20': [124], 'ppm.': [125, 157], 'Results': [126], 'With': [127], 'both': [128, 163, 243], 'forward': [129], 'random': [131], 'database': [132], 'searches': [133], 'FDR': [135], '≤1%': [136], 'at': [137, 151], 'spectrum': [139, 144], 'level,': [140], 'most': [142], 'protein': [143, 147, 234], 'matches': [145], 'IDs': [148], '15': [156, 240], 'average': [159], 'precursor': [164, 245], 'product': [166, 247], 'ions': [167], 'from': [168], 'representative': [170], 'high,': [171], 'medium,': [172], 'low': [174], 'abundance': [175], 'proteins': [176, 182], 'well': [178], 'common': [181], 'identified': [183], 'all': [185], '18': [187], 'replicate': [188], 'runs': [189], 'found': [191, 237, 261], '0–4': [194], 'ppm;': [195], 'no': [197, 255], 'significant': [198, 256], 'drift': [199, 257], 'measured': [201], 'observed': [205], 'within': [206, 262], 'calibration': [208, 251], 'period': [209], '1': [211], 'week.': [212], 'Conclusions': [213], 'Despite': [214], 'stated': [225], 'by': [226], 'manufacturer,': [228], 'identification': [235], 'ions.': [248], 'Weekly': [249], 'appropriate': [253], 'because': [254], '6-day': [264], 'period.': [265], 'Copyright': [266], '©': [267], '2016': [268], 'John': [269], 'Wiley': [270], '&': [271], 'Sons,': [272], 'Ltd.': [273]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2404105891', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-09-19T17:41:43.077911', 'created_date': '2016-06-24'}