Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2400937968', 'doi': 'https://doi.org/10.1016/j.neuroscience.2016.05.047', 'title': 'Protective effect of lithium chloride against hypoglycemia-induced apoptosis in neuronal PC12 cell', 'display_name': 'Protective effect of lithium chloride against hypoglycemia-induced apoptosis in neuronal PC12 cell', 'publication_year': 2016, 'publication_date': '2016-08-01', 'ids': {'openalex': 'https://openalex.org/W2400937968', 'doi': 'https://doi.org/10.1016/j.neuroscience.2016.05.047', 'mag': '2400937968', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27241942'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.neuroscience.2016.05.047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30122339', 'display_name': 'Neuroscience', 'issn_l': '0306-4522', 'issn': ['0306-4522', '1873-7544'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087025634', 'display_name': 'Yuzhen Xu', 'orcid': 'https://orcid.org/0000-0002-1289-3438'}, 'institutions': [{'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuzhen Xu', 'raw_affiliation_strings': ['Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210144482', 'https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057540096', 'display_name': 'Qian Wang', 'orcid': 'https://orcid.org/0000-0002-5031-0686'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qian Wang', 'raw_affiliation_strings': ['Department of Central Laboratory, The Central Hospital of Tai’an, Taishan Medical College, Tai’an, Shandong Province, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Central Laboratory, The Central Hospital of Tai’an, Taishan Medical College, Tai’an, Shandong Province, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100440895', 'display_name': 'Dongsheng Li', 'orcid': 'https://orcid.org/0000-0001-5348-4764'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Dongsheng Li', 'raw_affiliation_strings': ['School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039585748', 'display_name': 'Zhenghua Wu', 'orcid': 'https://orcid.org/0000-0001-8639-9689'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhenghua Wu', 'raw_affiliation_strings': ['School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100324938', 'display_name': 'Dawei Li', 'orcid': 'https://orcid.org/0000-0001-9150-5159'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Dawei Li', 'raw_affiliation_strings': ['School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088657272', 'display_name': 'Kaili Lu', 'orcid': 'https://orcid.org/0000-0002-0440-3048'}, 'institutions': [{'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kaili Lu', 'raw_affiliation_strings': ['Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210144482', 'https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100744163', 'display_name': 'Yuwu Zhao', 'orcid': 'https://orcid.org/0000-0001-5847-7715'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}, {'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yuwu Zhao', 'raw_affiliation_strings': ['Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930', 'https://openalex.org/I4210144482']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064440091', 'display_name': 'Yongning Sun', 'orcid': 'https://orcid.org/0000-0002-7675-1367'}, 'institutions': [{'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yongning Sun', 'raw_affiliation_strings': ['Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210144482', 'https://openalex.org/I183067930']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5100744163'], 'corresponding_institution_ids': ['https://openalex.org/I183067930', 'https://openalex.org/I4210144482'], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.48, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.927208, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '330', 'issue': None, 'first_page': '100', 'last_page': '108'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic Islet Dysfunction and Regeneration', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic Islet Dysfunction and Regeneration', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11171', 'display_name': 'Genetics and Pathogenesis of Type 1 Diabetes', 'score': 0.9923, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10560', 'display_name': 'Management of Diabetes Mellitus and Hypoglycemia', 'score': 0.9897, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hypoglycemia', 'display_name': 'Hypoglycemia', 'score': 0.579432}, {'id': 'https://openalex.org/keywords/continuous-glucose-monitoring', 'display_name': 'Continuous Glucose Monitoring', 'score': 0.526704}, {'id': 'https://openalex.org/keywords/diabetes', 'display_name': 'Diabetes', 'score': 0.524445}], 'concepts': [{'id': 'https://openalex.org/C2780668416', 'wikidata': 'https://www.wikidata.org/wiki/Q202758', 'display_name': 'Hypoglycemia', 'level': 3, 'score': 0.8478054}, {'id': 'https://openalex.org/C25498285', 'wikidata': 'https://www.wikidata.org/wiki/Q1981368', 'display_name': 'Neuroprotection', 'level': 2, 'score': 0.7782022}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.7154129}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.63620126}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.51767635}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.47320005}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.41991347}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40845558}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.39476752}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.35960966}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.33007568}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.32868832}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.28758866}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.20462921}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D018021', 'descriptor_name': 'Lithium Chloride', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D018696', 'descriptor_name': 'Neuroprotective Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053148', 'descriptor_name': 'Caspase 3', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D053148', 'descriptor_name': 'Caspase 3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004353', 'descriptor_name': 'Drug Evaluation, Preclinical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045022', 'descriptor_name': 'Lactate Dehydrogenases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045022', 'descriptor_name': 'Lactate Dehydrogenases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018021', 'descriptor_name': 'Lithium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018696', 'descriptor_name': 'Neuroprotective Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016716', 'descriptor_name': 'PC12 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060888', 'descriptor_name': 'Real-Time Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060449', 'descriptor_name': 'Wnt Signaling Pathway', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060449', 'descriptor_name': 'Wnt Signaling Pathway', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D060449', 'descriptor_name': 'Wnt Signaling Pathway', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.neuroscience.2016.05.047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30122339', 'display_name': 'Neuroscience', 'issn_l': '0306-4522', 'issn': ['0306-4522', '1873-7544'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27241942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.81}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': 'NSFC31271125'}], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1555712369', 'https://openalex.org/W1584279734', 'https://openalex.org/W1966004542', 'https://openalex.org/W1967013681', 'https://openalex.org/W1968263278', 'https://openalex.org/W1970005206', 'https://openalex.org/W1979533444', 'https://openalex.org/W1981735684', 'https://openalex.org/W1987044491', 'https://openalex.org/W1987349521', 'https://openalex.org/W1988438999', 'https://openalex.org/W1994928797', 'https://openalex.org/W1999444936', 'https://openalex.org/W2000115470', 'https://openalex.org/W2000462597', 'https://openalex.org/W2002021248', 'https://openalex.org/W2002856863', 'https://openalex.org/W2005504991', 'https://openalex.org/W2005874129', 'https://openalex.org/W2010578119', 'https://openalex.org/W2020888164', 'https://openalex.org/W2033120338', 'https://openalex.org/W2056933419', 'https://openalex.org/W2060325948', 'https://openalex.org/W2065309729', 'https://openalex.org/W2073707788', 'https://openalex.org/W2074425310', 'https://openalex.org/W2077112901', 'https://openalex.org/W2084243617', 'https://openalex.org/W2086693995', 'https://openalex.org/W2088751102', 'https://openalex.org/W2088863630', 'https://openalex.org/W2089485990', 'https://openalex.org/W2101427076', 'https://openalex.org/W2105082514', 'https://openalex.org/W2105291845', 'https://openalex.org/W2106134852', 'https://openalex.org/W2107353084', 'https://openalex.org/W2109416725', 'https://openalex.org/W2130253196', 'https://openalex.org/W2133540952', 'https://openalex.org/W2143413851', 'https://openalex.org/W2151238576', 'https://openalex.org/W2167674018', 'https://openalex.org/W2206536916', 'https://openalex.org/W2503091415', 'https://openalex.org/W3143098674', 'https://openalex.org/W4230487626', 'https://openalex.org/W4254695749'], 'related_works': ['https://openalex.org/W4295886409', 'https://openalex.org/W2995727304', 'https://openalex.org/W2365516742', 'https://openalex.org/W2165132828', 'https://openalex.org/W2095198015', 'https://openalex.org/W2077655479', 'https://openalex.org/W2034773528', 'https://openalex.org/W1988725105', 'https://openalex.org/W1593223226', 'https://openalex.org/W1517805603'], 'abstract_inverted_index': {'Hypoglycemia': [0], 'is': [1, 13, 49], 'defined': [2], 'by': [3, 125, 138, 150], 'an': [4], 'arbitrary': [5], 'plasma': [6], 'glucose': [7], 'level': [8], 'lower': [9], 'than': [10], '3.9mmol/L': [11], 'and': [12, 17, 60, 75, 85, 89, 110, 114, 131], 'a': [14, 38, 70], 'most': [15], 'common': [16], 'feared': [18], 'adverse': [19], 'effect': [20], 'of': [21, 23, 46, 63, 80, 119, 141, 162, 188], 'treatment': [22, 45], 'diabetes': [24], 'mellitus.': [25], 'Emerging': [26], 'evidences': [27], 'demonstrated': [28], 'that': [29, 95, 179], 'hypoglycemia': [30, 71, 105], 'could': [31], 'induce': [32], 'enhanced': [33, 108], 'apoptosis.': [34], 'Lithium': [35], 'chloride': [36], '(LiCl),': [37], 'FDA': [39], 'approved': [40], 'drug': [41], 'clinically': [42], 'used': [43], 'for': [44], 'bipolar': [47], 'disorders,': [48], 'recently': [50], 'proven': [51], 'having': [52], 'neuroprotection': [53, 182], 'against': [54, 82, 98, 183], 'various': [55], 'stresses': [56], 'in': [57, 73, 101, 107], 'the': [58, 77, 86, 111, 120, 139, 160, 163, 189], 'cellular': [59, 88, 113], 'animal': [61], 'models': [62], 'neural': [64], 'disorders.': [65], 'Here,': [66], 'we': [67], 'have': [68], 'established': [69], 'model': [72], 'vitro': [74], 'assessed': [76], 'neuroprotective': [78], 'efficacy': [79], 'LiCl': [81, 96, 157, 180], 'hypoglycemia-induced': [83, 99, 184], 'apoptosis': [84, 109, 146, 185], 'underlying': [87, 112], 'molecular': [90, 115], 'mechanisms.': [91], 'Our': [92], 'studies': [93], 'showed': [94], 'protects': [97], 'neurotoxicity': [100], 'vitro.': [102], 'Exposure': [103], 'to': [104, 153, 171, 173], 'results': [106, 177], 'mechanisms': [116], 'involved': [117], 'inhibition': [118], 'canonical': [121, 190], 'Wnt': [122, 164, 191], 'signaling': [123, 192], 'pathway': [124, 165], 'decreasing': [126], 'wnt3a': [127], 'levels,': [128, 134], 'β-catenin': [129], 'levels': [130], 'increasing': [132], 'GSK-3β': [133], 'which': [135, 167], 'was': [136], 'confirmed': [137], 'use': [140], 'Wnt-specific': [142], 'activator': [143], 'LiCl.': [144], 'Hypoglycemia-induced': [145], 'were': [147, 168], 'significantly': [148], 'reversed': [149], 'LiCl,': [151], 'leading': [152], 'increased': [154], 'cell': [155], 'survival.': [156], 'also': [158], 'alters': [159], 'expression/levels': [161], 'genes/proteins,': [166], 'reduced': [169], 'due': [170], 'exposed': [172], 'hypoglycemia.': [174], 'Overall,': [175], 'our': [176], 'conclude': [178], 'provides': [181], 'via': [186], 'activation': [187], 'pathway.': [193]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2400937968', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2024-08-15T14:20:32.305598', 'created_date': '2016-06-24'}