Publication Information

{'id': 'https://openalex.org/W2400815690', 'doi': 'https://doi.org/10.4269/ajtmh.1992.47.112', 'title': 'Emergence of Multidrug-Resistant Plasmodium Falciparum in Thailand: In Vitro Tracking', 'display_name': 'Emergence of Multidrug-Resistant Plasmodium Falciparum in Thailand: In Vitro Tracking', 'publication_year': 1992, 'publication_date': '1992-07-01', 'ids': {'openalex': 'https://openalex.org/W2400815690', 'doi': 'https://doi.org/10.4269/ajtmh.1992.47.112', 'mag': '2400815690', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1636877'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.4269/ajtmh.1992.47.112', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100045985', 'display_name': 'American Journal of Tropical Medicine and Hygiene', 'issn_l': '0002-9637', 'issn': ['0002-9637', '1476-1645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315658', 'host_organization_name': 'American Society of Tropical Medicine and Hygiene', 'host_organization_lineage': ['https://openalex.org/P4310315658'], 'host_organization_lineage_names': ['American Society of Tropical Medicine and Hygiene'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5058079190', 'display_name': 'Chansuda Wongsrichanalai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210112607', 'display_name': 'Armed Forces Research Institute of Medical Science', 'ror': 'https://ror.org/023swxh49', 'country_code': 'TH', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801080794', 'https://openalex.org/I4210112607', 'https://openalex.org/I4387156032']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'C Wongsrichanalai', 'raw_affiliation_strings': ['Department of Immunology and Biochemistry, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology and Biochemistry, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.', 'institution_ids': ['https://openalex.org/I4210112607']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113753194', 'display_name': 'H K Webster', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'H K Webster', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079117537', 'display_name': 'T Wimonwattrawatee', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'T Wimonwattrawatee', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040861308', 'display_name': 'P Sookto', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'P Sookto', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028951502', 'display_name': 'N Chuanak', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'N Chuanak', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090475973', 'display_name': 'Krongthong Thimasarn', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'K Thimasarn', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112167793', 'display_name': 'W.H. Wernsdorfer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'W H Wernsdorfer', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 9.033, 'has_fulltext': False, 'cited_by_count': 54, 'citation_normalized_percentile': {'value': 0.910767, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '47', 'issue': '1', 'first_page': '112', 'last_page': '116'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.909, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/halofantrine', 'display_name': 'Halofantrine', 'score': 0.9259488}], 'concepts': [{'id': 'https://openalex.org/C2777199930', 'wikidata': 'https://www.wikidata.org/wiki/Q736270', 'display_name': 'Mefloquine', 'level': 4, 'score': 0.98966885}, {'id': 'https://openalex.org/C2777498558', 'wikidata': 'https://www.wikidata.org/wiki/Q947595', 'display_name': 'Halofantrine', 'level': 5, 'score': 0.9259488}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.90649927}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.82305175}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.4981408}, {'id': 'https://openalex.org/C2777425658', 'wikidata': 'https://www.wikidata.org/wiki/Q422438', 'display_name': 'Chloroquine', 'level': 3, 'score': 0.45243955}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44385067}, {'id': 'https://openalex.org/C133936738', 'wikidata': 'https://www.wikidata.org/wiki/Q643839', 'display_name': 'Multiple drug resistance', 'level': 3, 'score': 0.4179207}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.40677708}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3486666}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.20900416}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.16457468}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': True}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D010616', 'descriptor_name': 'Phenanthrenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012044', 'descriptor_name': 'Regression Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013785', 'descriptor_name': 'Thailand', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.4269/ajtmh.1992.47.112', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100045985', 'display_name': 'American Journal of Tropical Medicine and Hygiene', 'issn_l': '0002-9637', 'issn': ['0002-9637', '1476-1645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315658', 'host_organization_name': 'American Society of Tropical Medicine and Hygiene', 'host_organization_lineage': ['https://openalex.org/P4310315658'], 'host_organization_lineage_names': ['American Society of Tropical Medicine and Hygiene'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1636877', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W7239210', 'https://openalex.org/W2474217646', 'https://openalex.org/W24292539', 'https://openalex.org/W2402403221', 'https://openalex.org/W2400815690', 'https://openalex.org/W2277080938', 'https://openalex.org/W2144038468', 'https://openalex.org/W2027560783', 'https://openalex.org/W1998937714', 'https://openalex.org/W1972177048'], 'abstract_inverted_index': {'Mefloquine': [0], 'was': [1, 19, 80], 'introduced': [2], 'into': [3], 'Thailand': [4, 125], 'in': [5, 21, 32, 38, 50, 61, 66, 91, 102, 114, 123], '1985': [6], 'for': [7, 82, 117], 'the': [8, 51, 55, 68, 103, 118, 132], 'treatment': [9, 119], 'of': [10, 17, 27, 41, 54, 72, 78, 97, 120], 'Plasmodium': [11], 'falciparum': [12, 28, 43, 121], 'infection.': [13], 'Recently,': [14], 'clinical': [15], 'failure': [16], 'mefloquine': [18, 62, 98], 'observed': [20, 81], 'southeastern': [22, 52, 124], 'Thailand,': [23], 'where': [24], 'an': [25, 84], 'epidemic': [26], 'malaria': [29, 122], 'occurred.': [30], 'Beginning': [31], '1984': [33], 'and': [34, 70, 99, 134], 'continuing': [35], 'until': [36, 64], '1989,': [37], 'vitro': [39, 94], 'monitoring': [40], 'P.': [42], 'isolates': [44], 'from': [45], 'Borai,': [46], 'a': [47, 58, 111], 'border': [48], 'district': [49], 'part': [53], 'country,': [56], 'showed': [57], 'progressive': [59], 'decrease': [60], 'sensitivity': [63, 95], '1989;': [65], '1990,': [67], 'degree': [69], 'prevalence': [71], 'resistance': [73, 79], 'accelerated.': [74], 'A': [75], 'similar': [76], 'pattern': [77], 'halofantrine,': [83], 'antimalarial': [85], 'drug': [86], 'not': [87], 'yet': [88], 'commercially': [89], 'available': [90, 115], 'Thailand.': [92], 'In': [93], 'patterns': [96], 'halofantrine': [100], 'elsewhere': [101], 'country': [104, 133], 'remained': [105], 'relatively': [106], 'unchanged.': [107], 'These': [108], 'observations': [109], 'suggest': [110], 'serious': [112], 'deterioration': [113], 'drugs': [116], 'that': [126], 'is': [127], 'predicted': [128], 'to': [129], 'spread': [130], 'throughout': [131], 'Southeast': [135], 'Asia.': [136]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2400815690', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-08T20:56:48.213964', 'created_date': '2016-06-24'}