Title: [Human parathyroid hormone (1-34) as a new therapeutic agent for osteoporosis].
Abstract: Human parathyroid hormone (PTH) is used clinically for severe osteoporosis in North America and Europe. The clinical trial is now in progress in Japan. In this review, I introduce the additive effects of PTH with bone resorption inhibitors, the different effects on bone structure and quality between PTH and bone resorption inhibitor, and the bone-increasing effects of PTH involved in IGF/IRS, AP-1 and Wnt pathways. I focus on new topics including the presentations in ASBMR (American Society for Bone and Mineral Research) 2004.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: review
Indexed In: ['pubmed']
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Cited By Count: 1
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