Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2399589569', 'doi': None, 'title': 'Role of proopiomelanocortin neurons and peptides in the regulation of energy homeostasis.', 'display_name': 'Role of proopiomelanocortin neurons and peptides in the regulation of energy homeostasis.', 'publication_year': 2004, 'publication_date': '2004-01-01', 'ids': {'openalex': 'https://openalex.org/W2399589569', 'mag': '2399589569', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15481808'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15481808', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5089080274', 'display_name': 'Malcolm J. Low', 'orcid': 'https://orcid.org/0000-0002-9900-3708'}, 'institutions': [{'id': 'https://openalex.org/I2802707198', 'display_name': 'Vollum Institute', 'ror': 'https://ror.org/054hm6j14', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2802707198']}, {'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Low Mj', 'raw_affiliation_strings': ['Vollum Institute, Department of Behavioral Neuroscience, and Center for the Study of Weight Regulation and Associated Disorders, Oregon Health and Science University, Portland, OR 97239-3098, USA.'], 'affiliations': [{'raw_affiliation_string': 'Vollum Institute, Department of Behavioral Neuroscience, and Center for the Study of Weight Regulation and Associated Disorders, Oregon Health and Science University, Portland, OR 97239-3098, USA.', 'institution_ids': ['https://openalex.org/I2802707198', 'https://openalex.org/I165690674']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5089080274'], 'corresponding_institution_ids': ['https://openalex.org/I2802707198', 'https://openalex.org/I165690674'], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.903, 'has_fulltext': False, 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.54472, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '27', 'issue': '6 Suppl', 'first_page': '95', 'last_page': '100'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10489', 'display_name': 'Neuroendocrine Regulation of Appetite and Body Weight', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10489', 'display_name': 'Neuroendocrine Regulation of Appetite and Body Weight', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/proopiomelanocortin', 'display_name': 'Proopiomelanocortin', 'score': 0.9698992}, {'id': 'https://openalex.org/keywords/energy-homeostasis', 'display_name': 'Energy homeostasis', 'score': 0.82635206}, {'id': 'https://openalex.org/keywords/homeostasis', 'display_name': 'Homeostasis', 'score': 0.54889476}, {'id': 'https://openalex.org/keywords/melanocortin-system', 'display_name': 'Melanocortin System', 'score': 0.504722}, {'id': 'https://openalex.org/keywords/melanocortins', 'display_name': 'Melanocortins', 'score': 0.45788044}], 'concepts': [{'id': 'https://openalex.org/C2781309135', 'wikidata': 'https://www.wikidata.org/wiki/Q418896', 'display_name': 'Proopiomelanocortin', 'level': 3, 'score': 0.9698992}, {'id': 'https://openalex.org/C2491326', 'wikidata': 'https://www.wikidata.org/wiki/Q5377024', 'display_name': 'Energy homeostasis', 'level': 3, 'score': 0.82635206}, {'id': 'https://openalex.org/C2779993316', 'wikidata': 'https://www.wikidata.org/wiki/Q6591465', 'display_name': 'Melanocortin', 'level': 3, 'score': 0.8086608}, {'id': 'https://openalex.org/C2778458369', 'wikidata': 'https://www.wikidata.org/wiki/Q253246', 'display_name': 'Arcuate nucleus', 'level': 3, 'score': 0.7345461}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5546848}, {'id': 'https://openalex.org/C63645605', 'wikidata': 'https://www.wikidata.org/wiki/Q103191', 'display_name': 'Homeostasis', 'level': 2, 'score': 0.54889476}, {'id': 'https://openalex.org/C2777003273', 'wikidata': 'https://www.wikidata.org/wiki/Q164386', 'display_name': 'Hypothalamus', 'level': 2, 'score': 0.51608723}, {'id': 'https://openalex.org/C2780090379', 'wikidata': 'https://www.wikidata.org/wiki/Q419119', 'display_name': 'Prohormone', 'level': 3, 'score': 0.51400745}, {'id': 'https://openalex.org/C3018667095', 'wikidata': 'https://www.wikidata.org/wiki/Q3455903', 'display_name': 'Glucose homeostasis', 'level': 4, 'score': 0.51369584}, {'id': 'https://openalex.org/C118303440', 'wikidata': 'https://www.wikidata.org/wiki/Q419968', 'display_name': 'Neuropeptide', 'level': 3, 'score': 0.47318506}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.46567032}, {'id': 'https://openalex.org/C2909567013', 'wikidata': 'https://www.wikidata.org/wiki/Q6591465', 'display_name': 'Melanocortins', 'level': 4, 'score': 0.45788044}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.44808617}, {'id': 'https://openalex.org/C102230213', 'wikidata': 'https://www.wikidata.org/wiki/Q430117', 'display_name': 'Transgene', 'level': 3, 'score': 0.42655998}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.40291786}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.38135388}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.30453572}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17638338}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.12866911}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.111150086}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C2777391703', 'wikidata': 'https://www.wikidata.org/wiki/Q1053470', 'display_name': 'Insulin resistance', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C511355011', 'wikidata': 'https://www.wikidata.org/wiki/Q12174', 'display_name': 'Obesity', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009479', 'descriptor_name': 'Neuropeptides', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D011333', 'descriptor_name': 'Pro-Opiomelanocortin', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D024506', 'descriptor_name': "5' Flanking Region", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024506', 'descriptor_name': "5' Flanking Region", 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009479', 'descriptor_name': 'Neuropeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009479', 'descriptor_name': 'Neuropeptides', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010902', 'descriptor_name': 'Pituitary Gland', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010902', 'descriptor_name': 'Pituitary Gland', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011333', 'descriptor_name': 'Pro-Opiomelanocortin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011333', 'descriptor_name': 'Pro-Opiomelanocortin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001615', 'descriptor_name': 'beta-Endorphin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001615', 'descriptor_name': 'beta-Endorphin', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D001615', 'descriptor_name': 'beta-Endorphin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15481808', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Affordable and clean energy', 'id': 'https://metadata.un.org/sdg/7', 'score': 0.71}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3009050400', 'https://openalex.org/W2979374415', 'https://openalex.org/W2469427743', 'https://openalex.org/W2399589569', 'https://openalex.org/W2136943612', 'https://openalex.org/W2122579758', 'https://openalex.org/W2107263774', 'https://openalex.org/W2091225147', 'https://openalex.org/W1987922392', 'https://openalex.org/W1981396719'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2399589569', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-08-31T08:31:11.854472', 'created_date': '2016-06-24'}