Title: The Role of chTLR4 and its Signaling Pathway in Chicken with LPS-induced Lymphocytes
Abstract: Toll-like receptor 4 is the transmembrane receptor of lipopolysaccharides(LPS),it mediates a variety of injury response induced by LPS.The experiments on chicken lymphocytes induced by LPS with 6,12,24,48 h,to show IL-1β,NF-κB levels,as in-depth study of intracellular TLR4-mediated LPS signaling basis.The results showed that LPS induced cells,IL-1β,NF-κB content increased,both reached the maximum at 24 h,and then began to decreased.The groups in 12,24 h were significantly higher than the control groups(P0.05),the groups in 6,48 h groups were not significantly higher than the control groups(P0.05).
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot