Title: Relationship between Non-alcoholic Fatty Liver Disease and Insulin Resistance in Patients with Type 2 Diabetes Mellitus
Abstract: Objective To investigate the relationship between non-alcoholic fatty liver(NAFLD)and insulin resistance in type 2 diabetes(T2DM)patients.Methods All of 98 cases diagnosed as type 2 diabetes were divided into two groups:T2DM combined without NAFLD group and T2DM combined with NAFLD group.The general information and laboratory serum markers were measured.Results In 98 cases of type 2 diabetes,compared with T2DM combined without NAFLD,the levels of body mass index(BMI),fasting plasma glucose(FPG),fasting serum insulin(FInS),homeostatic model assessment of insulin resistance(HOMA-IR),serum total cholesterol(TC),triglycerides(TG),low density lipoprotein cholesterol(LDL-C)and uric acid(UA)were all significantly increased in T2DM combined with NAFLD(P0.05);the level of high-density lipoprotein cholesterol(HDL-C) was obviously decreased in T2DM with NAFLD,compared with T2DM combined without NAFLD(P0.05).Conclusion T2DM combined with NAFLD had higher level of insulin secretion and more significant insulin resistance than T2DM combined without NAFLD insulin resistance.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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