Title: Evaluation of the radiofrequency ablation lesions in canine prostate with real-time harmonic gray-scale contrast-enhanced ultrasonography
Abstract: Objective To assess the radiofrequency ablation (RFA) lesions in canine prostate with real-time harmonic gray-scale contrast-enhanced ultrasonography and investigate the feasibility to predict these lesions. Methods A total of 5 male beagle dogs took RFA of the prostate. Radiofrequency (RF) was delivered under transrectal ultrasound (TRUS) guidance. A lesion was created in the right and left lateral lobes of canine prostate,respectively. The examination of conventional gray-scale ultrasonography,power Doppler ultrasonography,real-time harmonic gray-scale contrast-enhanced ultrasonography were performed immediately after RF procedure. All animals were subsequently sacrificed and the prostates were harvested for pathologic analysis. Thermal lesion volume was calculated based on expected shape of ellipsoid using equation. The volumes of the calculated thermal lesion on contrast-enhanced ultrasonography in dogs were compared with the volumes obtained from the pathological specimens. ResultsThe RFA lesions could not be imaged accurately with real-time conventional gray-scale or power Doppler ultrasonography. However,contrast-enhanced low MI perfusion imaging was able to have real-time monitoring for the lesion (no blood flow). The volume of lesions was measured with contrast-enhanced ultrasonography without significant difference with those of pathologic results. Ultrasonic imaging(conventional gray-scale or power Doppler sonography)of the ablation areas also had its own characteristics. Conclusion The real-time harmonic gray-scale contrast-enhanced ultrasonography appears to be an accurate modality for assessment of RFA lesions. Conventional gray-scale and power Doppler sonography had their own characteristics to evaluate the RFA lesion.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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