Title: Determination of residual organic solvents in Shicha Ganmao Capsule by gas chromatography with headspace sampling
Abstract: Objective To establish a method for determination of the seven residual organic solvents(n-hexane,benzene,toluene,o-dimethylbenzene,p-dimethylbenzene,styrene and divinyl benzene)in Shicha Ganmao Capsule.Methods Gas chromatography with headspace sampling was applied to the study.Agilent HP-INNOWAX silica capillary column was 30 m × 1.0 mm,0.53 μm.The initial temperature was kept at 30 ℃ for 5 min,then the temperature was raised to 200 ℃ at the rate of 10 ℃/min and subsequently sustained for 5 min.FID detector temperature was 250 ℃.The vial temperature was 70 ℃,and the vial time was 30 min.Results There was a good linearity in the experimental concentration(r= 0.999 4~0.999 8).The RSD was all less than 5.0%.The average recovery rates were in the range of 99.16%~102.0%.Conclusion The analytical method is simple,accurate and sensitive.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot