Title: The pathological types of patients with renal insufficiency.
Abstract: Objective To study the pathological types and features of patients with clinical chronic renal insufficiency(Scr≥130μmol/L).Methods Total 104 patients who were admitted to our hospital with chronic renal insufficiency and received renal biopsy from January 2006 to December 2008 were enrolled in thte study.Clinical manifestations and pathological features were analyzed.Results There were 104 CKD patients with increased serum creatinine before renal biopsy,about 11.9% of all patients received renal biopsy in our department.The averageserum creatinine was(235.1±114.4)μmol/L.The original diseases were chronic glomerulonephritis(63 cases),nephrotic syndrome(27 cases),systemic vasculitis(4cases),and systemic lupus erythematosus(3 cases).There were 78 patients(75.0%)with hypertension.The pathological types were IgA nephropathy(46.2%,70.8% with proliferative sclerosing glomerulonephritis),interstitial nephritis,mesangial proliferative glomemlonephritis,cresccntic glomerulonephritis,focal segmental glomerulosclerosis,and type IV lupus nephritis.The patients with proliferative sclerosing IgA nephropathy usually had more severe hypertention and lower proteinuria.Conclusion The main pathological type of chronic renal insufficiency patient is IgA nephropathy,of which proliferative sclerosing nephritis is the most,and interstitial nephritis is the sccond common type.Chronic kidney lesions are main pathological findings.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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