Abstract: The rapid development of yeast two-hybrid and immuno-affinity purification make the study of protein-protein interaction in a large scale at the proteome level possible.At present,studies on human protein-protein interaction network in cell,tissue,organ,and even whole body have been doing successively.and the protein number in the protein-protein interaction network have increased from several to whole proteome.The studies of protein-protein interaction network about function,disease and ecology have made some achievements.However,there are also some questions and challenges in the present study.This paper reviews the research methods of the proteinprotein interaction network,the research progress and challenges,and points out the orientation and target of research of the human protein-protein interaction network.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot