Title: The imaging characteristics of intracranial demyelinating pseudotumors and correlation with clinical pathology(reports of 3 cases and review of relevant literature)
Abstract: Objective To evaluate imaging features of brain demyelinating pseudotumors(DPT) and correlation with clinical pathological finding.Methods The MR imaging features of 3 patients confirmed by bioscopy were analyzed,the correlation of imaging features with clinical pathological findings were evaluated and reviewed the MRI features of relevant literature.Results 3 cases(2 males and 1 female) with DPT were analyzed,aged 24 to 68 years old.There was no definite antecedent and the clinical syndromes were atypical.2 of 3 cases showed solitary lesions in cerebral frontal lobe and temporal lobe respectively,and 1 case showed multiple lesions in cerebral hemisphere.On T2WI,the lesions showed low-density or iso-density,and on T1WI the lesions showed low density.The lesions appeared half-round and patch enhancement on MR contrast-enhancement scan,and 1 case appeared slight hemorrhage around the lesions.All patients with diffusion weighted imaging(DWI) showed high density.The typical pathological changes were demyelination,perivascular inflammatory infiltration and reactive gliosis.The cteutzfeuldt cells could be found in most patients.Conclusion DPT has some characteristic MRI imaging features,most of the lesions occurred in or near the cerebral superficies of white mater,contrast enhancement MRI and diffusion weighted imaging(DWI) were useful technique in the DPT diagnosis and differential diagnosis with other tumors.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot