Title: Study on the feasibility of treatment of femoral neck fractures in the young and middle aged through YUKUAN PILL instead of YUKUAN DRINK
Abstract:Objective:To compare the clinical curative effects of YUKUAN PILL with that of YUKUAN DRINK in the treatment of femoral neck fractures(FNF) in the young and middle aged,and to explore the feasibility ...Objective:To compare the clinical curative effects of YUKUAN PILL with that of YUKUAN DRINK in the treatment of femoral neck fractures(FNF) in the young and middle aged,and to explore the feasibility of YUKUAN PILL in the treatment of FNF instead of YUKUAN DRINK.Methods:One hundred young and middle aged patients with FNF were randomly divided into YUKUAN PILL group(group YP)and YUKUAN DRINK group(group YD),50 cases in each group.All the patients in the 2 groups were processed with open reduction and internal fixation with hollow screw and bone grafting of iliac flap with deep circumflex iliac vessel pedicle.Patients in group YP were administrated with YUKUAN PILL on the day after the operation,while the others in group YD were administrated with YUKUAN DRINK on the same day.Six months later,the symptoms and signs,clinical curative effects and safety were compared between the 2 groups.Results:①There was no statistical difference in symptoms and signs between the 2 groups(Z=-1.035,P=0.301).②There was no statistical difference in clinical curative effects between the 2 groups(Z=-4.234,P=0.662).③During the treatment period,one patient with epigastric discomfort were found in group YP and relieved after changing the administration time to postprandial 30 minutes,and two patients with stomach fullness and one patient with diarrhea were found in group YD.There was no statistical difference in incidence of adverse reaction between the 2 groups(P=0.617).Conclusion:YUKUAN PILL can maintain original effectiveness and safety of YUKUAN DRINK.Meanwhile,those problems caused by backward dosage form were solved.As a result,YUKUAN PILL can take the place of YUKUAN DRINK in the clinic.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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