Title: Determination of genpioside,baicalin and berberine hydrochloride in Gonglao Quhuo Tablets simultaneously by RP-HPLC
Abstract: AIM: To establish a method of determining genpioside,baicalin and berberine in Gonglao Quhuo Tablets(Caulis Mahoniae,Cortex Phellodendri Chinensis,Radix Scutellariae,etc). METHODS: The mobile phase composed of A acetonitrile,B acetonitrile and 0.5% triethylamine(Ph3.1)(10∶90).The flow rate was 1.0 mL/min with the wavelength at 254 nm. RESULTS:The calibration curves were linear in the ranges of 3.22-206 μg/mL(r=0.999 9) for genpioside,2.95-186 μg/mL(r=0.999 9) for baicalin and 1.64-104 μg/mL(r=0.999 9) for berberine hydrochloride,respectively.The average recoveries were not less than 98.4%. CONCLUSION: This HPLC method is convenient,rapid,accurate and could be used for quality control of production of Gonglao Quhuo Tablets.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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