Title: Pattern and predictive factors of LevelIIb lymph nodes metastasis in patients with cN1b papillary thyroid carcinoma
Abstract: Objective To evaluate the frequency and pattern of levelⅡb lymph nodes(LNs)metastasis and identify the risk factors for levelⅡb LNs in papillary thyroid carcinoma(PTC)patients with positive lateral neck LNs.Methods We retrospectively reviewed the medical records between June 2007 and June 2011 of 83 patients with PTC who underwent therapeutic lateral neck dissections(levelⅡ-Ⅴ).Neck dissection specimens were obtained for histologic analysis for node metastasis with respect to the individual neck levels.Results 45 (54.2%),58(69.9%),61(73.5%)and 13(15.7%)patients had histologically positive lymph nodes in levelsⅡ,Ⅲ,ⅣandⅤ,respectively.Metastases in levelⅡa andⅡb were observed in 43(51.8%)and 12 (14.5%)patients,respectively.In multivariate analysis,simultaneous multilevel involvement(levelⅡa,Ⅲ, andⅣ)of lymphatic metastases was associated with levelⅡb metastasis(37.5%vs.5.1%,OR=10.8,P= 0.032).Conclusions Lymphatic metastases are not common in levelⅡb in PTC patients,LevelⅡb lymph- adenectomy may be omitted if simultaneous multilevel involvement(levelⅡa,Ⅲ,andⅣ)of lymphatic metastases are not found by pathology or CT scan.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot