Title: The clinical understanding of ulinastatin in the therapy about acute pancreatitis
Abstract: Objective To approach the difference about ulinastatin using minipump intravenous infusion and not using minipump in the therapy about acute pancreatitis.discuss the proper dose of ulinastatin.Methods 94 severe acute pancreatitis patients were divided into 2 groups.The experiment group(46 cases)intravenous infused ulinastatin through the minipump,and the control group(48 cases)did not use the minipump.The clinical symptom,physical sign,laboratory data and the long-term complications are compared.Results ①The experiment group patients'symptom and physical sign such as abdominal pain,abdominal distension and tenderness disappear faster than the control group(P 0.05).②The 3-days blood amylase(BA),7days blood amylase,urinary amylase,blood sugar,white blood cell of the experiment group are all lower than the control group(P 0.05).③The happening rate of pancreatic pseudocyst between two groups has no difference(P 0.05),it is relate to using growth hormone release inhibiting hormone or not(P 0.05).Conclusion The curative effect of ulinastatin using minipump in the therapy about acute pancreatitis is fine,and the dose is little.combining growth hormone release inhibiting hormone is suggested to prevent the long-term complication.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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