Title: Experimental study of the prev ention effect of transcutaneous electrical nerve stimulation on denervated muscl e atrophy after end-to-side neurorrhaphy
Abstract: Objec tive:To study the effect of transcutaneous electrical nerve stimulation(TENS)on preventing the denervated muscle atrophy and peripheral nerve regeneration afte r end-to-side neurorrhaphy in rabbit model.Method:Eighteen five-month-old New Z ealand rabbits were randomly divided into three groups.The peroneal nerve was tr ansected and then its distal end was sutured to the tibial nerve which had been windowed by means of end-to-side attachment at2cm above the knee in both hind li mbs.The left hindlimb served as the experimental side that accepted TENS and the right hindlimb as the control side.The toe-extension reflex,anterior tibial mus cle wet weight,histological and electrophysiological tests were examined at3,6an d16weeks postoperatively.Result:All the above mentioned indices in the experime ntal side were much better than those in the control side(P0.05or P0.01)exc ept the wet weight of A group and the latency of C group(P0.05).Conclusion:TEN S can effectively prevent denervated muscle from atrophy and promote the rate of peripheral nerve collateral sprouting after end-to-side neurorrhaphy to a certa in extent.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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