Title: Experimental Study of Effect of Sodium Hyaluranate to Prevent Postoperative Abdominal Adhesion
Abstract: Objective To evaluate the effect of sodium hyaluranate to prevent postoperative abdominal adhesion and explore their mechanism. Methods Total 38 Wistar rats were divided into 2 groups r andomly:Group A(blank Control), Group B(use sodium hyaluranate).They were daubed with physiological saline solution and sodium hyaluranate respectively on the injured abdomen cavity.On the day 21 after operation, we observed the abdomen cavity adhesion when the rats were executed. Results There are 0 rat with 0 level adhesion,1 rat with I level adhesion, 1 rat with II level,5 rats with III level adhesion, and 7 rats with IV level adhesion in group A. Comparatively, There are 6 rats with 0 level adhesion,7 rats with I level adhesion, 2 rats with II level,1 rat with III level adhesion, and 0 rat with IV level adhesion in group B. The extent and area of adhesion in two groups are different significantly(P0.05). Conclusion Sodium hyaluranate can reduce the extent of postoperative abdominal adhesion obviously,and thus provide a simple and effective methods to prevent postoperative abdominal adhesion and complication.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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