Title: Detection and significance of cytokines in cervicovaginal lavage fluid in patients with bacterial vaginosis and vulvovaginal candidiasis
Abstract: Objective To improve the diagnosis and treatment level of bacterial vaginosis(BV) and vulvovaginal candidiasis(VVC).Methods Cervicovaginal lavage fluid was collected from 35 healthy women in child-bearing age(control group),35 patients with BC(BV group),35 patients with VVC(VVC group).The level of cytokines(IL-2,IL-8,IFN-γ,IL-4,IL-13,IL-10,IgE)of the three groups were detected by ELISA.Results Compared with the control group,the IL-2 of BV group decreased significantly,IL-13,IL-4,IL-10 increased significantly,IL-8,IFN-γ,IgE had no significant change;the IFN-γ of VVC group decreased significantly,IL-2,IL-13,IL-4,IgE increased obviously,IL-8,IL-10 had no significant change.Conclusions The un-balance of Th1/Th2 is common in BV and VVC,detecting the changes of local cytokine is helpful for controling their inflammation better.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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