Title: Influence of entecavir on hepatic function of chronic hepatitis B in the near future
Abstract: Objective:To study the influence of entecavir on hepatic function chronic hepatitis B in the near future.Methods: Changes of ALT, HBV DNA, symptom, objective sign mutation of 60 patients at 4,8,12 weeks before and after entecavir were determined. Results: Two groups patients' symptom and objective sign were fundamental relief and showed no significant(P0.05);the ALT of treated group showed great significant than control group at 4 weeks(P0.01),the ALT of treated group showed great significant lesser than control group at 12 weeks(P0.05),the ALT of treated group were increased prominently and showed great significant higher than control group at 4 weeks(P0.01),HBV DNA mutation of treated group showed great significant higher than control group at 4,8,12 weeks(P0.01).Conclusion: Entecavir is effective though the mutations and breakthrough are present.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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