Publication Information

{'id': 'https://openalex.org/W2390056579', 'doi': None, 'title': '[Cardioprotective effects of NOS and PKC under hemin induced ischemia/reperfusion injury in rat hearts].', 'display_name': '[Cardioprotective effects of NOS and PKC under hemin induced ischemia/reperfusion injury in rat hearts].', 'publication_year': 2007, 'publication_date': '2007-05-01', 'ids': {'openalex': 'https://openalex.org/W2390056579', 'mag': '2390056579', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21179764'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://europepmc.org/abstract/MED/21179764', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110258140', 'display_name': 'He-Jing Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'He-jing Xu', 'raw_affiliation_strings': ['Department of Physiology, Wenzhou Medical College, Wenzhou 325027, China)'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, Wenzhou Medical College, Wenzhou 325027, China)', 'institution_ids': ['https://openalex.org/I27781120']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101050142', 'display_name': 'Pingping Lv', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ping-ping Lv', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045580230', 'display_name': 'Li Zhu', 'orcid': 'https://orcid.org/0000-0002-7804-907X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Li Zhu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100659787', 'display_name': 'Yang Wang', 'orcid': 'https://orcid.org/0000-0003-3444-901X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yang Wang', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084039687', 'display_name': 'Yue‐Liang Shen', 'orcid': 'https://orcid.org/0000-0002-6110-1329'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yue-liang Shen', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100394760', 'display_name': 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'https://openalex.org/W2022580005', 'https://openalex.org/W2015812865', 'https://openalex.org/W2003937760', 'https://openalex.org/W1992369944', 'https://openalex.org/W1984933001', 'https://openalex.org/W1665122892'], 'abstract_inverted_index': {'AIM': [0], 'Whether': [1], 'hemin,': [2], 'a': [3], 'heme': [4], 'oxygenase': [5], '1': [6], '(HO-1)': [7], 'inducer,': [8], 'reduces': [9], 'ischemia/reperfusion': [10, 50, 89], 'injury': [11], 'and': [12, 17, 47, 83, 94, 106, 181], 'whether': [13], 'NO': [14, 179], 'synthase': [15, 180], '(NOS)': [16], 'PKC': [18], 'are': [19], 'involved': [20], 'in': [21, 27, 69, 78, 81, 86, 108, 115, 188, 192], 'the': [22, 28, 76, 87, 109, 120, 137, 143, 166, 176], 'cardioprotective': [23], 'effects': [24], 'were': [25, 52], 'investigated': [26], 'present': [29], 'study.': [30], 'METHODS': [31], 'The': [32, 41, 102], 'Langendorff': [33], 'model': [34], 'of': [35, 60, 104, 131, 139, 150, 153, 178], 'isolated': [36, 88, 193], 'rat': [37, 70, 100, 117, 194], 'heart': [38], 'was': [39, 112, 123], 'used.': [40], 'ventricular': [42], 'function,': [43], 'infarct': [44, 121], 'size,': [45], 'LDH': [46, 105], 'CK': [48, 107], 'during': [49], 'period': [51], 'also': [53, 164], 'observed.': [54], 'RESULTS': [55], '(1)': [56], 'After': [57], 'intraperitoneal': [58], 'injection': [59], 'hemin': [61, 140, 161], '(50': [62], 'mg/kg)': [63, 159], 'for': [64, 91, 97], '24': [65], 'h,': [66], 'COHb': [67], 'concentration': [68], 'blood': [71], 'enhanced.': [72], 'He-min': [73], 'preconditioning': [74, 162], 'prevented': [75], 'increase': [77], 'LVEDP,': [79], 'decrease': [80], 'LVDP': [82], '+/-': [84], 'dP/dt(max)': [85], '(ischemia': [90], '30': [92], 'main': [93], 'subsequent': [95], 'reperfusion': [96], '2': [98], 'h)': [99], 'hearts.': [101, 118, 195], 'leakage': [103], 'coronary': [110], 'effluent': [111], 'significantly': [113], 'declined': [114], 'hemin-treated': [116], 'And': [119], 'size': [122], 'als': [124], 'reduced.': [125], '(2)': [126], 'By': [127], 'using': [128], 'an': [129, 151], 'inhibitor': [130, 152], 'NOS': [132], 'NG-nitro-L-arginine': [133], 'methyl': [134], 'ester': [135], 'before': [136, 160], 'administration': [138], 'could': [141, 163], 'inhibit': [142], 'protection': [144], 'induced': [145, 168], 'by': [146, 169], 'hemin.': [147, 170], '(3)': [148], 'Administration': [149], 'protein': [154, 182], 'kinase': [155, 183], 'C': [156, 184], 'chelerythrine': [157], '(1': [158], 'abolish': [165], 'cardioprotection': [167, 191], 'CONCLUSION': [171], 'These': [172], 'data': [173], 'suggest': [174], 'that': [175], 'involvement': [177], 'have': [185], 'been': [186], 'implicated': [187], 'hemin-induced': [189], 'delayed': [190]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2390056579', 'counts_by_year': [], 'updated_date': '2024-12-08T15:01:29.645657', 'created_date': '2016-06-24'}