Title: The Influence of Ulinastain on TNF-αand IL-1βin Serum of Rats with Inflammatory Factor as Pancreas Ischemical Reperfusion Injury
Abstract: Objective To investigate whether ulinastain can inhibit rat inflammatory factor when pancreas ischemical reperfusion injury.Metheds 72 SD rats were grouped randomly into three groups:sham group,I/R group and ulinastain group.We detected TNF-α,IL-β at 0 h,6 h,12 h and 24 h when rats were under pancreas ischemia reperfusion injury.Results Compared with sham group and ulinastain group,I/R group had higher TNF-α obviously at only time(P0.05);compared with sham group,ulinastain group and I/R group had higher IL-β obviously at 6 h,12 h,24 h(P0.05),but the ulinastain group's increased level lower obviously than I/R group(P0.05).Conclusions As pancreas ischemical reperfusion injury,ulinastain can inhibit rat inflammatory factors and has protective effects.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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