Title: Correlation between ambulatory blood pressure and severity of coronary artery stenosis
Abstract: Objective To study the correlation between different ambulatory blood pressure monitoring(ABPM) parameters and severity of coronary heart disease.Methods A total of 212 patients with suspicious coronary heart disease(CHD) receiving coronary angiography and 24 hours ABPM were divided into lesion group(n=169) and non-lesion group(n=43) according to coronary artery lesion,and were divided into single-vessel disease group(n=56),double-vessel disease group(n=38) and triple-vessel group(n=75) according to coronary artery lesion range.The ABPM parameters were compared among these groups.Results The levels of 24-hour average systolic blood pressure,24-hour average pulse pressure,day average pulse pressure,day average systolic blood pressure,night average systolic blood pressure,night average pulse pressure,high systolic blood pressure and the low systolic blood pressure were higher in lesion group than those in non-lesion group(P0.05),and increased with the increased number of stenosis vessels,especially significantly in triple vessel group(P0.05).The levels of day average diastolic blood pressure,night average diastolic blood pressure,24-hour average diastolic blood pressure and high diastolic blood pressure were lower in the lesion group than those in the non-lesion group(P0.05),and had the tendency of inversely decrease with the increased number of stenosis vessel,but it had no significant difference(P0.05).The prevalence of double-vessel and triple-vessel disease was significantly higher in non-dipper,anti-dipper,over-dipper blood pressure pattern than that in normal dipper pattern blood pressure pattern(P0.05).Multiple regression analysis showed night average systolic blood pressure had the independent predicting value to coronary artery disease.Conclusion The night average pulse pressure and high systolic blood pressure are closely correlated with severity of coronary heart disease.The night systolic blood pressure is the best parameter for predicting coronary heart disease.Ambulatory blood pressure change in the pattern is an important factor for coronary artery disease.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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