Title: Analysis of the performance of imatinib and interferon combined with chemotherapy for chronic myeloid leukemia
Abstract: Objective:To investigate the efficacy of imatinib and interferon combined with chemotherapy for chronic myeloid leukemia(CML).Methods:From June 2004 to July 2009,58 patients newly diagnosed CML in chronic phase with philadelphia chromosome positive wererandomly divided into two groups,imatinib group and interferon-chemotherapy group.The clinical effects were compared between the two groups.Results:The total effective rate of two groups was not statistically different(P0.05).The complete hematologic remission rate,complete cytogenetic remission rate,complete molecular effect rate and 5-year survival rate were higher in the imatinib group than in the interferon-chemotherapy group(P0.05).Conclusion:Both imatinib and interferon-chemotherapy are effective treatments for CML in chronic phase.Individual treatment scheme should be designed for patients depend on the situation.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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