Title: Clinical research of hypertension and hypercholesterolemia induced carotid arteriosclerosis
Abstract: [Objective]To test and compare the role of hypertension and hypereholesterolemia in carotid atherosderosis(CAS),and evaluate the significant effect of hypertension on CAS.[Methods]Sixty cases of normal population,60 cases of hypercholesterdemia,and 60 cases of hypertension complicated with hyperlipemia,as well as 180 cases of hypertension patients(60 cases of each level) were selected as the study objects from Dec 2010-Dec 2012 in Xiantao First People's Hospital.Color Doppler ultrasound was put into practice respectively to detect intima media thickness(IMT) of carotid artery and the incidence of plaque.[Results]The IMT value in hyperlipemia group,hypertension complicated with hypercholesterolemia group and hypertension group were higher than that in normal group,with significant difference(P 0.01).The incidence of carotid artery plaque in hyperlipemia group,hypertension complicated with hypercholesterolemia group and hypertension group were higher than that in normal group,with significant difference(P 0.01).The IMT values and the incidence of carotid artery plaque in hyperlipemia group were higher than that in hypertension group,without significant difference(P 0.05).The IMT values and the incidence of carotid artery plaque in Stage 1 hypertension group was not significantly different with normal group(P 0.05).The IMT values in Stage 2 hypertension group was lower than that in hyperlipemia group,with significant difference(P 0.05),the incidence of carotid artery plaque in Stage 3 hypertension group was higher than hyperlipemia group,without significant difference(P 0.05).The IMT values and the incidence of carotid artery plaque in Stage 3 hypertension group was significantly different with that in hyperlipemia group(P 0.05).[Conclusion]Hypertension and hyperlipemia have an equally important role in inducing CAS.Stage 3 hypertension has more significant effect than hypercholesterolemia in inducing CAS.It is more significant that good control of blood pressure,especially in patients with Stage 3 hypertension,can slow down the process of atherosclerosis and reduce even prevent the occurrence of CAS than lipid dropping,which can not be ignored
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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