Title: On the Curative Effect of α-Chymotrypsin on the Residual Pleural Thickening Caused by Pleural Cavity Infection
Abstract: Objective To observe the local curative effect of α-chymotrypsin on the residual pleural thickening(RPT)caused by pleural cavity infection.Method Forty cases of RPT patients were randomly divided into treatment group and control group,(20 cases in each group).Microtubule drainage in the pleural cavity was performed in two groups.The patient in the treatment group were given 4 000 U α-chymotrypsin dissolved in 20mL sodium chloride and the patients in the control group were only treated with the microtubule drainage.The thickness of pleura,the size of residual cavity and the time with the tube were measured and recorded before and after the treatment.Results The pleural thickness of the patients in the treatment group after the injection of α-chymotrypsin was significantly reduced compared with that in the control group(t=3.071,P0.01);the size of residual cavity in the treatment group after the treatment was significantly different from that in the control group(t=-8.82,P0.05).The mean time with the catheterization in the treatment group was 7.25±2.53 days and that in the control group was 5.90±2.07 days,which showed that the difference in the mean time between two groups was significantly different(t=2.339,P0.05).Conclusion The curative effect of α-chymotrypsin on the pleural thickening caused by pleural cavity infection is significant,the method is simple,safe and efficient,and low-cost.The method is worthy to be popularized in clinic.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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