Title: The clinical significance of LDH and β_2-MG measuring in patients with non-Hodgkin's lymphoma
Abstract:Objective:To evaluate the clinical significance of the serum lactic dehydrogenate (LDH) and β 2-Microglobulin (β 2-MG) measuring in Non-Hodgkin's Lymphoma(NHL) patients.Method:The LDH and β 2-MG are c...Objective:To evaluate the clinical significance of the serum lactic dehydrogenate (LDH) and β 2-Microglobulin (β 2-MG) measuring in Non-Hodgkin's Lymphoma(NHL) patients.Method:The LDH and β 2-MG are collected from 69 NHL patients and measured by rate method and radioimmunoassay respectively.Result:All samples are classified into phase Ⅰ~Ⅱ or phase Ⅲ~Ⅳ, group A or group B, without or with NHL cells in bone marrow and chemotherapy complete remission or chemotherapy partial remission (CR or PR) accordingly for comparison purpose. It is found that the value of LDH and β 2-MG for all patients in the later category of the comparison pair mentioned above are obviously higher than that in their comparison counterpart and the difference is of significance (P 0.05), while the difference for chemotherapy ineffective group before and after chemotherapy seems of less significance (P 0.05).Conclusion:The level of LDH and β 2-MG can be taken as an auxiliary clinical index to classify the phase, existence of NHL cells in bone marrow, prognosis and effectiveness of treatment in NHL patients.Read More
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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