Title: Effect of Allicin on Antioxidant in Serum of Diabetic Rats
Abstract: Objective To observe the antioxidant effect of allicin( AL) on serum of streptozotocin( STZ)-induced diabetic rats. Methods Hyperglycemia was induced in normal Wistar rats by intraperitoneal injection of STZ( 40mg / kg). After three days of STZ induction,the hyperglycemic rats were treated with AL by intraperitoneal injection at different doses for 28 days. The rats were divided into five groups: The control group,diabetic group,AL groups( low,middle and high dose). The activity of superoxide dismutase( SOD) and catalase( CAT) were measured,as well as the level of malonaldehyde( MDA) in serum. Results The results showed that AL could observably enhance the activity of SOD and CAT and decrease MDA level in serum of diabetic rats in a dose-dependent manner. Conclusion AL has remarkable antioxidant effect in serum of diabetic rats.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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Cited By Count: 2
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