Title: The result analysis of second trimester prenatal screening in Panzhihua city
Abstract: Objective:To analyze the prenatal screening/diagnosis in Panzhihua in 2 years and a half.Method:Serum samples were collected on middle period singleton pregnancy(15~20+6 week) and free-βhCG and AFP level were determined.Then the high-risk population of prenatal screening,who were offered genetic counseling,if they agree to,were diagnosed by amniotic fluid cytology.Results:Among 6907 pregnant women,288 cases were high risk.The positive rate was 4.17%.253 cases were accepted amniotic fluid cytology,and the rate was 62.84%.2 cases of fetal chromosomal abnormalities were found,of which 1 case of Down syndrome,1 case of trisomy 18.After tracking follow-up,there were 28 cases adverse pregnancy happened.In 2 years and a half,there were 3 cases who were false negative,the rate was 0.45‰.Conclusions:Second trimester prenatal screening/diagnosis is to prevent birth defects and improve the birth quality.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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