Publication Information

{'id': 'https://openalex.org/W2386940891', 'doi': None, 'title': 'Cytosolic phospholipase A_2 involved in epidermal growth factor and fetal bovine serum-induced proliferation in Hela cells and its activity and expression', 'display_name': 'Cytosolic phospholipase A_2 involved in epidermal growth factor and fetal bovine serum-induced proliferation in Hela cells and its activity and expression', 'publication_year': 2008, 'publication_date': '2008-01-01', 'ids': {'openalex': 'https://openalex.org/W2386940891', 'mag': '2386940891'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCZL200810002.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764664221', 'display_name': 'Chinese Clinical Oncology', 'issn_l': '2304-3865', 'issn': ['2304-3865', '2304-3873'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310321814', 'host_organization_name': 'AME Publishing Company', 'host_organization_lineage': ['https://openalex.org/P4310321814'], 'host_organization_lineage_names': ['AME Publishing Company'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047972319', 'display_name': 'Jiao Shun-chan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Jiao Shun-chan', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5047972319'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 63}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10748', 'display_name': 'Growth Hormone and Insulin-like Growth Factors', 'score': 0.9653, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10748', 'display_name': 'Growth Hormone and Insulin-like Growth Factors', 'score': 0.9653, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Research', 'score': 0.9642, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10966', 'display_name': 'Liver physiology and pathology', 'score': 0.9625, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hela', 'display_name': 'HeLa', 'score': 0.83892655}, {'id': 'https://openalex.org/keywords/fetal-bovine-serum', 'display_name': 'Fetal bovine serum', 'score': 0.7819888}], 'concepts': [{'id': 'https://openalex.org/C2777366897', 'wikidata': 'https://www.wikidata.org/wiki/Q847482', 'display_name': 'HeLa', 'level': 3, 'score': 0.83892655}, {'id': 'https://openalex.org/C2779404806', 'wikidata': 'https://www.wikidata.org/wiki/Q488614', 'display_name': 'Fetal bovine serum', 'level': 3, 'score': 0.7819888}, {'id': 'https://openalex.org/C2776362946', 'wikidata': 'https://www.wikidata.org/wiki/Q424374', 'display_name': 'Epidermal growth factor', 'level': 3, 'score': 0.7124837}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.58940345}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.5769072}, {'id': 'https://openalex.org/C2776415932', 'wikidata': 'https://www.wikidata.org/wiki/Q48743', 'display_name': 'Western blot', 'level': 3, 'score': 0.5103821}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4961489}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.46553105}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.46316895}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.45209932}, {'id': 'https://openalex.org/C2778597717', 'wikidata': 'https://www.wikidata.org/wiki/Q420248', 'display_name': 'Phospholipase C', 'level': 3, 'score': 0.445408}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42921722}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.4124904}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.34868392}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.30986863}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.28544295}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.15442619}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.104367495}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCZL200810002.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764664221', 'display_name': 'Chinese Clinical Oncology', 'issn_l': '2304-3865', 'issn': ['2304-3865', '2304-3873'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310321814', 'host_organization_name': 'AME Publishing Company', 'host_organization_lineage': ['https://openalex.org/P4310321814'], 'host_organization_lineage_names': ['AME Publishing Company'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2473777288', 'https://openalex.org/W2412997514', 'https://openalex.org/W2412674696', 'https://openalex.org/W2385004586', 'https://openalex.org/W2362139341', 'https://openalex.org/W2358003611', 'https://openalex.org/W2354629150', 'https://openalex.org/W2166299099', 'https://openalex.org/W2152875808', 'https://openalex.org/W2139073001', 'https://openalex.org/W2117022243', 'https://openalex.org/W2087561275', 'https://openalex.org/W2073383561', 'https://openalex.org/W2061291926', 'https://openalex.org/W2038186359', 'https://openalex.org/W2026753199', 'https://openalex.org/W2020457650', 'https://openalex.org/W2020147460', 'https://openalex.org/W2013722917', 'https://openalex.org/W198133572'], 'abstract_inverted_index': {'Objective:To': [0], 'explore': [1], 'effects': [2], 'of': [3, 31, 35, 46, 76, 80, 98, 105, 121, 142], 'cytosoloic': [4], 'phospholipase': [5], 'A2(cPLA2)': [6], 'on': [7, 117, 131, 163], 'epidermal': [8], 'growth': [9], 'factor(EGF)': [10], 'induced': [11, 16, 86], 'and': [12, 20, 23, 28, 41, 50, 55, 59, 69, 73, 89, 100, 127, 153], 'fetal': [13], 'bovine': [14], 'serum(FBS)': [15], 'Hela': [17, 47, 95, 110, 118, 155], 'cells': [18, 48, 119, 156], 'proliferation': [19, 85, 120], 'its': [21], 'activity': [22, 40, 58, 66, 79], 'expression.Methods:We': [24], 'used': [25], 'inhibitor': [26, 33, 72, 144], 'AACOCF3': [27], 'antisense': [29, 74, 122], 'oligodeoxynucleotide(ODN)': [30], 'cPLA2,and': [32, 81], 'U0126': [34], 'ERK1/2': [36, 101, 143, 158], 'to': [37, 161], 'inhibit': [38], 'cPLA2': [39, 65, 77, 99, 132], 'expression,and': [42], 'observed': [43], 'the': [44, 84, 112, 128], 'changes': [45], 'viabilities': [49], 'cell': [51, 103], 'cycle': [52], 'by': [53, 64, 87], 'CellTiter-Blue': [54], 'flow': [56], 'cytometry.Meanwhile,cPLA2': [57], 'expression': [60, 134], 'were': [61], 'also': [62], 'detected': [63], 'assay': [67], 'kit': [68], 'western': [70], 'blot.Results:Both': [71], 'ODN': [75, 123], 'suppressed': [78], 'obviously': [82], 'inhibited': [83], 'EGF': [88], 'FBS': [90], 'in': [91, 94, 136, 151], 'dose-dependent': [92, 138], 'manner': [93], 'cells.Both': [96], 'inhibitors': [97], 'decreased': [102], 'proportion': [104], 'G2/M': [106], 'obviously,and': [107], 'they': [108], 'blocked': [109], 'at': [111], 'S/G2': [113], 'boundary.Moreover,the': [114], 'inhibitory': [115, 129], 'effect': [116, 130], 'was': [124, 135, 145], 'most': [125], 'obvious': [126], 'protein': [133], 'a': [137], 'manner.The': [139], 'similar': [140], 'situation': [141], 'observed.Conclusion:cPLA2': [146], 'could': [147], 'play': [148], 'important': [149], 'roles': [150], 'EGF-': [152], 'FBS-induced': [154], 'proliferation,and': [157], 'probably': [159], 'contribute': [160], 'regulation': [162], 'this': [164], 'course.': [165]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2386940891', 'counts_by_year': [], 'updated_date': '2024-12-13T07:42:14.376993', 'created_date': '2016-06-24'}