Title: Characteristics of Uitrastructural Diagnosis of Hairy Cell Leukamia
Abstract:Objective To inquire into the characteristics of ultrastructural diagnosis of hairy cell leukamia (HCL). Methods Ultrastructural characteristics of hairy cell in the peripheral blood or bone marrow fr...Objective To inquire into the characteristics of ultrastructural diagnosis of hairy cell leukamia (HCL). Methods Ultrastructural characteristics of hairy cell in the peripheral blood or bone marrow from 7 cases with HCL were observed by transmission electron microscope (TEM). Results Hairy cell were seen under TEM. Its features included:①The featare of microvilli. There were numerous and long micmrovilli in surface of hairy cell. These Microvilli had same size in diameter and various shapes.②The feature of nucleus. The nucleus was oval and was lightly indented, and heterochromatins were distributed in inner surface of nuclear membrance.③The feaure of cytoplasm. There were rich organelles in cytoplasm. Ribosome-lamella complexes (R-LC) were not seen, but myelin figure body was firstly seen. Conclusion The features of microvilli of hairy cell are important characteristics of ultrastructural diagnosis of HLC. The features of nucleus and cytoplasm were reference characteristics of differential diagnosis of HCL.But R-LC was not certain for characteristics of diagnosis of HCL.Read More
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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