Title: The Value of Magnetic Resonance Diffusion Weighted Imaging in Hepatocellular Carcinoma
Abstract: Objective To determine an apparent diffusion coefficient(ADC) of hepatic lesions and to evaluate the value of the ADC in hepatocellular carcinoma.Methods Eighty-four patients of having hepatic lesions were examined by magnetic resonance(MR) at Philips Intera 1.5T superconducting MR system.There were hepatocellular carcinoma in 36 patients;hepatic metastases in 15 patients;hepatic cavemous hemangioma in 33 patients.All of DWI and conventional T1WI,T2WI T2/SPIR were obtained by using a body phased-array coil.The Diffusion Weighted Imaging were performed with single shot echo planar imaging(EPI) sequence.Then the ADC values of lesions and the ratio of the ADC values of lesion/liver were calculated.Results(1)The ADC values with hign b values were lower and more accurate than the ADC values with low b values,therefore,the average ADC values of hepatic lesions were the ADC values when the b was 500 s/mm2.(2)The average ADC values of hepatic lesions as follows:HCC(1.20±0.32)×10-3 mm2/s,HMC(1.57±0.42)×10-3 mm2/s,HCH(2.01±0.53)×10-3 mm2/s.The ADC values of benign lesions were higher than those of malignant(P0.05).The ADC values of HMC were not significantly different from the ADC values of HHC(P0.05).The ratio of the ADC values of lesion/liver in hepatocellular carcinoma and hepatic metastases was 1.10±0.17 and 1.55±0.21 respectively,there were significant different between both.Conclusion(1)The ADC values of benign lesions were higher than those of malignant lesions.The ADC values and DWI can help to differentiate benign from malignant hepatic lesions.(2)The study in hepatic lesions Using ADC value,the ratio of the ADC values of lesion/liver,would improve the accuracy in diagnosing hepatic lesions.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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