Title: Preparation and Biodistribution of ~(99)Tc~m-HEDTMP
Abstract:HEDTMP (N(2hydroxyethyl) ethlenediamine1,1,2tri(methylene phosphonic acid)) is labeled with 99Tcm. The stability, rabbit bone imaging and mice biodistribution of 99TcmHEDTMP are inves...HEDTMP (N(2hydroxyethyl) ethlenediamine1,1,2tri(methylene phosphonic acid)) is labeled with 99Tcm. The stability, rabbit bone imaging and mice biodistribution of 99TcmHEDTMP are investigated. The stability studies show that99TcmHEDTMP is stable in 5 h. The biodistribution indicate 99TcmHEDTMP is mainly concentrated on animal skeleton and the uptake of nontarget tissue is low. The results show that 99TcmHEDTMP is a potential promising bone imaging agent.Read More
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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