Title: Clinical observation coming from Donepezil uniting Nimodipine to treat vascular dementia(non-dementia)
Abstract:Objective To explore efficacy and safety treatment to vascular cognitive impairment(non-demented) with donepezil and nimodipine.Methods 62 cases of vascular cognitive impairment(non-demented) patients...Objective To explore efficacy and safety treatment to vascular cognitive impairment(non-demented) with donepezil and nimodipine.Methods 62 cases of vascular cognitive impairment(non-demented) patients were randomly divided into two groups;conventional anti-platelet aggregation,lipid adjustment,blood pressure control,blood sugar control and circular treatment improvement were done to the control group.Compared with control group,donepezil and nimodipine treatment were added to treatment group.MMSE,ADL and HDS were used to score10 weeks before and after treatment for evaluation.Results After 10 weeks of treatment,MMSE,ADL,HDS score of treatment group were significantly improved compared with this group before and after treatment.Significant improvement was seen that the control group(P0.05) was statistically significant and no significant untoward reactions was observed from the two groups.Conclusion Donepezil combined with nimodipine was proved as relatively effective and also observed clinically safer in the treatment of vascular cognitive impairment(non-demented).Read More
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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