Title: Therapeutic Effect of milrinone in Treatment of Refractory Heart Failure Patients
Abstract: Objective:To evaluate the effect of milrinone in treating refractory heart failure. Methods:5mg of milrinone in 250ml of 5% Glucose or 0.9% NaCl Solution were given daily by intravenous drip to 56 cases of refractory heart failure for a period of consecutive 7 days. The symptoms and signs were observed before and after the treatment, heart rate, blood pressure and heart function examined by Doppler echocardiography. Results:a. The total effective rate was 85.7%. b. The left ventricular ejection fraction (LVEF) and fraction shortening (FS) were increased significantly ( P 0.01) after treatment. The rate of filling velocity in early diastole (E) over that in late diastole (A) was increased significantly ( P 0.05). Conclusion:Milrinone has good effect for treating refractory heart failure. It improves not only the cardiac systolic function but also the diastolic function.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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