Title: Clinical observation of Tongxinluo capsule on subcortical arteriosclerotic encephalopathy
Abstract: Objective To observe the therapeutic effect of Tongxinluo capsule on subcortical arteriosclerotic encephalopathy(SAE).Methods Consecutive 126 cases of SAE were randomly divided into control(62 cases) and treatment(64 cases) groups.Control group was given aspirin and conventional treatment,and treatment group was given Tongxinluo capsule based on the conventional therapy.The change in mini mental state examination (MMSE) and functional activities qestionnaire(FAQ) were observed and compared on intellectual and living ability before and after treatment in both two groups,while the indexes of blood lipids,platelet aggregation,plasma fibrinogen and high sensitivity C-reactive protein were detected.Results After 6 months,the FAQ and MMSE scores and the blood parameters in treatmenl group were improved significantly than those in the control group(P0.05).At the end of follow up period,the cerebral vascular events in treatment group was 9.4%(6/64),lower than that in the control group 22.6%(14/62,P0.01).Conclusion Combination Tongxinluo capsule with conventional treatment could further improve the cognitive function and living ability in the patients with SAE,as well as reduce the incidence of cerebrovascular events.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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