Title: Comparative study on moxifloxacin and levofloxacin in treating senile patients with respiratory tract bacterial infections
Abstract: Objective To compare the efficacy and safety of moxifloxacin and levofloxacin in treating respiratory tract bacterial infections in the senile patients.Methods Eighty-six senile patients with respiratory tract bacterial infections were randomly divided into two groups.The clinical trial group with moxifloxacin 400 mg once a day,orally for 7-10 days and the control group with levofloxacin 200 mg twice a day for 7-10 days.Results The total clinical effective rate in the clinical trial group was significantly higher than that in the control group(P0.01).The recovery rate of the clinical trial group(68.18%) and the effective rate(95.45%) were significantly higher than that of the control group(33.33% and 76.19%,P0.01).The clinical trial group was better than the control group at the eradication rates of pathogens(93.54% and 72.41%) and sensitivity of drugs(96.77% and 75.86%),the difference had the statistical significance(P0.05).The rate of adverse reaction was 4.55% in the clinical trial group and 7.14% in the control group,respectively.Conclusion Moxifloxacin is an effective and safe antibacterial drug in treating respiratory tract bacterial infections in the senile patients.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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