Title: MRI Evaluation of Leptomeningeal Metastases
Abstract: Objective To discuss the anatomic basis, transfer pathway and MRI features of leptomeningeal metastases. Methods Axial, sagittal T1WI, T2WI and axial FLAIR plain scans were performed in 29 patients. Axial, sagittal T1WI and coronal T1WI fat suppression after injection of Gd-DTPA 0.2mol/kg were taken. Results Both cerebral metastases and leptomeningeal linear thickening were seen in 17.24%, cerebral metastases with leptomeningeal nodular or linear thickening in 24.14%, leptomeningeal nodular and linear thickening in 13.79%, leptomeningeal nodules in 6.90%, leptomeningeal linear thickening in 13.79%, linear thickening of ependyma and leptomeninge in 13.79%,cerebral and leptomeningeal as well as cranial nerve metastases in 10.34%. Conclusion Both hematogenous and CSF metastases occur at the leptomeningeal membrane depending on its anatomic basis and blood supply. MRI examinations with Gd-DTPA must be done in patients with malignant tumor in case of missed diagnosis.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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