Title: Preliminary study on injection speed of perfusion in solitary pulmonary nodule with 64-detector CT
Abstract: Objective:To investigate on the effect of injection speed of contrast media in the perfusion of solitary pulmonary nodule.Methods:Prospective studies on CT perfusion with 64-detector CT were performed in 50 patients with solitary pulmonary nodules.Male 34 cases and female 16 cases with the age ranging 28~73 years,average age 56.02±9.11 years.Among all the cases,43 cases were pathologically proved with operation;2 cases with CT-guided biopsy,1 case with bronchofibroscope and 4 cases with metastasis.50 patients were divided randomly into two groups with 3.5 ml/s injection speed respectively.Results:In the two groups,blood flow(P=0.2490.05);blood volume(P=0.7370.05);mean transit time(P=0.7760.05);permeably surface(P=0.4540.05).In group one,blood flow was 49.006±42.429 ml·100g-1·min-1;blood volume was 3.358±4.608 ml/100g;mean transit time was 6.307±3.772s;permeably surface was 9.378±9.040 ml·100g-1·min-1 in group two,blood flow was 52.917±61.206 ml·100g-1·min-1,blood volume was 3.045±4.671 ml/100g,mean transit time was 6.079±3.831s,permeably surface was 8.142±7.082 ml·100g-1·min-1.There was no significant difference between the two groups of different injection speeds in SPN CT perfusion(P0.05).Conclusion:No dramatic influence was found for different injection speed in CT perfusion of solitary pulmonary nodules.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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