Title: EXPERIMENTAL STUDY ON HYALURONIC ACID AND FIBRIN SEALANT INHIBITING SKIN SCAR
Abstract: Objective To probe the effect of HA of two concentrations and fibrin sealant on the wound healing of SD rat.Methods 16 male SD rats were used for this study.Four 1cm length incisions performed in each rat was respectively served as control,1%HA,1.4%HA,fibrin sealant group.Fibroblast,collagen content and tension were measured.Result In HA and fibrin sealant group,the inflamatory cell appeared less than control,the epithelia looked like normal skin,the conllagn was more randomly organized.There weren't different in the tension strength of the wound.Conclusion HA inhibited the proliferation of fibroblast,decreased the collagen content.Fibrin sealant could inhibited scar through machine of endocrine homeostasis and adhensive property.
Publication Year: 1999
Publication Date: 1999-01-01
Language: en
Type: article
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